The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 47: PTS system mannitol-specific transporter subunit I...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein-phosphocysteine-mannitol phosphotransferase system transporter activity GO:0090565
Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + mannitol(out) = protein cysteine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
44 P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA)
(34 more)
Mannitol transmembrane transporter activity GO:0015575
Enables the transfer of mannitol from one side of a membrane to the other. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group.
7 Q9KKQ7 (/ISS) Q9KKQ7 (/ISS) Q9KKQ7 (/ISS) Q9KKQ7 (/ISS) Q9KKQ7 (/ISS) Q9KKQ7 (/ISS) Q9KKQ7 (/ISS)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phosphoenolpyruvate-dependent sugar phosphotransferase system GO:0009401
The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC.
74 P69826 (/ISA) P69826 (/ISA) P69826 (/ISA) P69826 (/ISA) P69826 (/ISA) P69826 (/ISA) P69826 (/ISA) P69826 (/ISA) P69826 (/ISA) P69826 (/ISA)
(64 more)
Phosphoenolpyruvate-dependent sugar phosphotransferase system GO:0009401
The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC.
44 P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA)
(34 more)
Phosphoenolpyruvate-dependent sugar phosphotransferase system GO:0009401
The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC.
44 P00550 (/IMP) P00550 (/IMP) P00550 (/IMP) P00550 (/IMP) P00550 (/IMP) P00550 (/IMP) P00550 (/IMP) P00550 (/IMP) P00550 (/IMP) P00550 (/IMP)
(34 more)
Mannitol transport GO:0015797
The directed movement of mannitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group.
44 P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA)
(34 more)
Mannitol transport GO:0015797
The directed movement of mannitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group.
44 P00550 (/IMP) P00550 (/IMP) P00550 (/IMP) P00550 (/IMP) P00550 (/IMP) P00550 (/IMP) P00550 (/IMP) P00550 (/IMP) P00550 (/IMP) P00550 (/IMP)
(34 more)
Phosphoenolpyruvate-dependent sugar phosphotransferase system GO:0009401
The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC.
7 Q9KKQ7 (/ISS) Q9KKQ7 (/ISS) Q9KKQ7 (/ISS) Q9KKQ7 (/ISS) Q9KKQ7 (/ISS) Q9KKQ7 (/ISS) Q9KKQ7 (/ISS)
Mannitol transport GO:0015797
The directed movement of mannitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group.
7 Q9KKQ7 (/ISS) Q9KKQ7 (/ISS) Q9KKQ7 (/ISS) Q9KKQ7 (/ISS) Q9KKQ7 (/ISS) Q9KKQ7 (/ISS) Q9KKQ7 (/ISS)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
118 P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA)
(108 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
74 P69826 (/RCA) P69826 (/RCA) P69826 (/RCA) P69826 (/RCA) P69826 (/RCA) P69826 (/RCA) P69826 (/RCA) P69826 (/RCA) P69826 (/RCA) P69826 (/RCA)
(64 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
44 P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA) P00550 (/IDA)
(34 more)
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