The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 221: Two component transcriptional regulator DevR

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
12 P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA)
(2 more)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
12 P9WMF9 (/IMP) P9WMF9 (/IMP) P9WMF9 (/IMP) P9WMF9 (/IMP) P9WMF9 (/IMP) P9WMF9 (/IMP) P9WMF9 (/IMP) P9WMF9 (/IMP) P9WMF9 (/IMP) P9WMF9 (/IMP)
(2 more)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
12 P9WMF9 (/IMP) P9WMF9 (/IMP) P9WMF9 (/IMP) P9WMF9 (/IMP) P9WMF9 (/IMP) P9WMF9 (/IMP) P9WMF9 (/IMP) P9WMF9 (/IMP) P9WMF9 (/IMP) P9WMF9 (/IMP)
(2 more)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
12 P9WMF9 (/IMP) P9WMF9 (/IMP) P9WMF9 (/IMP) P9WMF9 (/IMP) P9WMF9 (/IMP) P9WMF9 (/IMP) P9WMF9 (/IMP) P9WMF9 (/IMP) P9WMF9 (/IMP) P9WMF9 (/IMP)
(2 more)
Dormancy process GO:0022611
A developmental process in which dormancy (sometimes called a dormant state) is induced, maintained or broken. Dormancy is a suspension of most physiological activity and growth that can be reactivated.
12 P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA)
(2 more)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
12 P9WMF9 (/IGI) P9WMF9 (/IGI) P9WMF9 (/IGI) P9WMF9 (/IGI) P9WMF9 (/IGI) P9WMF9 (/IGI) P9WMF9 (/IGI) P9WMF9 (/IGI) P9WMF9 (/IGI) P9WMF9 (/IGI)
(2 more)
Cellular response to nitrosative stress GO:0071500
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.
12 A0A0H3LF05 (/IEP) A0A0H3LF05 (/IEP) A0A0H3LF05 (/IEP) A0A0H3LF05 (/IEP) A0A0H3LF05 (/IEP) A0A0H3LF05 (/IEP) A0A0H3LF05 (/IEP) A0A0H3LF05 (/IEP) A0A0H3LF05 (/IEP) A0A0H3LF05 (/IEP)
(2 more)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
12 P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA)
(2 more)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
12 P9WMF9 (/HDA) P9WMF9 (/HDA) P9WMF9 (/HDA) P9WMF9 (/HDA) P9WMF9 (/HDA) P9WMF9 (/HDA) P9WMF9 (/HDA) P9WMF9 (/HDA) P9WMF9 (/HDA) P9WMF9 (/HDA)
(2 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
12 P9WMF9 (/HDA) P9WMF9 (/HDA) P9WMF9 (/HDA) P9WMF9 (/HDA) P9WMF9 (/HDA) P9WMF9 (/HDA) P9WMF9 (/HDA) P9WMF9 (/HDA) P9WMF9 (/HDA) P9WMF9 (/HDA)
(2 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
12 P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA)
(2 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
12 P9WMF9 (/HDA) P9WMF9 (/HDA) P9WMF9 (/HDA) P9WMF9 (/HDA) P9WMF9 (/HDA) P9WMF9 (/HDA) P9WMF9 (/HDA) P9WMF9 (/HDA) P9WMF9 (/HDA) P9WMF9 (/HDA)
(2 more)
Host cell endosome lumen GO:0072493
The volume enclosed by the membranes of the host cell endosome.
12 P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA) P9WMF9 (/IDA)
(2 more)
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