The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Ribose-phosphate pyrophosphokinase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ribose phosphate diphosphokinase activity GO:0004749
Catalysis of the reaction: D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + 2 H(+).
182 Q60A16 (/ISS) Q74FE8 (/ISS) Q74FE8 (/ISS) Q81VZ0 (/ISS) Q81VZ0 (/ISS) Q81VZ0 (/ISS) Q81VZ0 (/ISS) Q81VZ0 (/ISS) Q81VZ0 (/ISS) Q81VZ0 (/ISS)
(172 more)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
116 P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA)
(106 more)
Ribose phosphate diphosphokinase activity GO:0004749
Catalysis of the reaction: D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + 2 H(+).
116 P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA)
(106 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
104 P0A717 (/IPI) P0A717 (/IPI) P0A717 (/IPI) P0A717 (/IPI) P0A717 (/IPI) P0A717 (/IPI) P0A717 (/IPI) P0A717 (/IPI) P0A717 (/IPI) P0A717 (/IPI)
(94 more)
Phosphate ion binding GO:0042301
Interacting selectively and non-covalently with phosphate.
104 P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA)
(94 more)
Manganese ion binding GO:0030145
Interacting selectively and non-covalently with manganese (Mn) ions.
12 P9WKE3 (/IDA) P9WKE3 (/IDA) P9WKE3 (/IDA) P9WKE3 (/IDA) P9WKE3 (/IDA) P9WKE3 (/IDA) P9WKE3 (/IDA) P9WKE3 (/IDA) P9WKE3 (/IDA) P9WKE3 (/IDA)
(2 more)
Ribose phosphate diphosphokinase activity GO:0004749
Catalysis of the reaction: D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + 2 H(+).
3 Q386K8 (/ISM) Q38A32 (/ISM) Q38A32 (/ISM)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Purine ribonucleotide biosynthetic process GO:0009152
The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
182 Q60A16 (/ISS) Q74FE8 (/ISS) Q74FE8 (/ISS) Q81VZ0 (/ISS) Q81VZ0 (/ISS) Q81VZ0 (/ISS) Q81VZ0 (/ISS) Q81VZ0 (/ISS) Q81VZ0 (/ISS) Q81VZ0 (/ISS)
(172 more)
5-phosphoribose 1-diphosphate biosynthetic process GO:0006015
The chemical reactions and pathways resulting in the formation of 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate.
104 P0A717 (/IMP) P0A717 (/IMP) P0A717 (/IMP) P0A717 (/IMP) P0A717 (/IMP) P0A717 (/IMP) P0A717 (/IMP) P0A717 (/IMP) P0A717 (/IMP) P0A717 (/IMP)
(94 more)
Histidine biosynthetic process GO:0000105
The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
52 Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC)
(42 more)
Tryptophan biosynthetic process GO:0000162
The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate.
52 Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC)
(42 more)
'de novo' IMP biosynthetic process GO:0006189
The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate.
52 Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC)
(42 more)
UMP biosynthetic process GO:0006222
The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate.
52 Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC)
(42 more)
5-phosphoribose 1-diphosphate biosynthetic process GO:0006015
The chemical reactions and pathways resulting in the formation of 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate.
12 P9WKE3 (/IDA) P9WKE3 (/IDA) P9WKE3 (/IDA) P9WKE3 (/IDA) P9WKE3 (/IDA) P9WKE3 (/IDA) P9WKE3 (/IDA) P9WKE3 (/IDA) P9WKE3 (/IDA) P9WKE3 (/IDA)
(2 more)
Purine ribonucleotide biosynthetic process GO:0009152
The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
3 Q386K8 (/ISM) Q38A32 (/ISM) Q38A32 (/ISM)
Nucleoside metabolic process GO:0009116
The chemical reactions and pathways involving a nucleoside, a nucleobase linked to either beta-D-ribofuranose (a ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleoside), e.g. adenosine, guanosine, inosine, cytidine, uridine and deoxyadenosine, deoxyguanosine, deoxycytidine and thymidine (= deoxythymidine).
2 Q38A32 (/ISM) Q38A32 (/ISM)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
104 P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA)
(94 more)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
12 P9WKE3 (/HDA) P9WKE3 (/HDA) P9WKE3 (/HDA) P9WKE3 (/HDA) P9WKE3 (/HDA) P9WKE3 (/HDA) P9WKE3 (/HDA) P9WKE3 (/HDA) P9WKE3 (/HDA) P9WKE3 (/HDA)
(2 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
12 P9WKE3 (/HDA) P9WKE3 (/HDA) P9WKE3 (/HDA) P9WKE3 (/HDA) P9WKE3 (/HDA) P9WKE3 (/HDA) P9WKE3 (/HDA) P9WKE3 (/HDA) P9WKE3 (/HDA) P9WKE3 (/HDA)
(2 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
6 Q38A32 (/IDA) Q38A32 (/IDA) Q57ZX2 (/IDA) Q57ZX2 (/IDA) Q57ZX2 (/IDA) Q57ZX2 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q4Q0M2 (/ISO) Q4QI56 (/ISO)
Plastid GO:0009536
Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.
2 O64888 (/IDA) O64888 (/IDA)
Glycosome GO:0020015
A membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis.
1 Q386K8 (/IDA)
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