The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Ribose-phosphate pyrophosphokinase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ribose phosphate diphosphokinase activity GO:0004749
Catalysis of the reaction: D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + 2 H(+).
197 Q54PA9 (/ISS) Q5ALK3 (/ISS) Q5ALK3 (/ISS) Q60A16 (/ISS) Q74FE8 (/ISS) Q74FE8 (/ISS) Q75JN8 (/ISS) Q81VZ0 (/ISS) Q81VZ0 (/ISS) Q81VZ0 (/ISS)
(187 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
120 P0A717 (/IPI) P0A717 (/IPI) P0A717 (/IPI) P0A717 (/IPI) P0A717 (/IPI) P0A717 (/IPI) P0A717 (/IPI) P0A717 (/IPI) P0A717 (/IPI) P0A717 (/IPI)
(110 more)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
104 P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA)
(94 more)
Ribose phosphate diphosphokinase activity GO:0004749
Catalysis of the reaction: D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + 2 H(+).
104 P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA)
(94 more)
Phosphate ion binding GO:0042301
Interacting selectively and non-covalently with phosphate.
104 P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA)
(94 more)
Ribose phosphate diphosphokinase activity GO:0004749
Catalysis of the reaction: D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + 2 H(+).
3 Q386K8 (/ISM) Q38A32 (/ISM) Q38A32 (/ISM)
Ribose phosphate diphosphokinase activity GO:0004749
Catalysis of the reaction: D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + 2 H(+).
2 Q5ALK3 (/IMP) Q5ALK3 (/IMP)
Ribose phosphate diphosphokinase activity GO:0004749
Catalysis of the reaction: D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + 2 H(+).
2 O94413 (/ISO) P87171 (/ISO)
Ribose phosphate diphosphokinase activity GO:0004749
Catalysis of the reaction: D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + 2 H(+).
2 Q5BBW5 (/RCA) Q5BBW5 (/RCA)

There are 24 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Purine ribonucleotide biosynthetic process GO:0009152
The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
182 Q60A16 (/ISS) Q74FE8 (/ISS) Q74FE8 (/ISS) Q81VZ0 (/ISS) Q81VZ0 (/ISS) Q81VZ0 (/ISS) Q81VZ0 (/ISS) Q81VZ0 (/ISS) Q81VZ0 (/ISS) Q81VZ0 (/ISS)
(172 more)
5-phosphoribose 1-diphosphate biosynthetic process GO:0006015
The chemical reactions and pathways resulting in the formation of 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate.
129 P0A717 (/IMP) P0A717 (/IMP) P0A717 (/IMP) P0A717 (/IMP) P0A717 (/IMP) P0A717 (/IMP) P0A717 (/IMP) P0A717 (/IMP) P0A717 (/IMP) P0A717 (/IMP)
(119 more)
Histidine biosynthetic process GO:0000105
The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
52 Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC)
(42 more)
Tryptophan biosynthetic process GO:0000162
The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate.
52 Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC)
(42 more)
'de novo' IMP biosynthetic process GO:0006189
The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate.
52 Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC)
(42 more)
UMP biosynthetic process GO:0006222
The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate.
52 Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC) Q48MV9 (/IGC)
(42 more)
5-phosphoribose 1-diphosphate biosynthetic process GO:0006015
The chemical reactions and pathways resulting in the formation of 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate.
25 P38063 (/IGI) P38063 (/IGI) P38063 (/IGI) P38063 (/IGI) P38063 (/IGI) P38063 (/IGI) P38620 (/IGI) P38620 (/IGI) P38620 (/IGI) P38620 (/IGI)
(15 more)
Fungal-type cell wall organization GO:0031505
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall.
25 P38063 (/IPI) P38063 (/IPI) P38063 (/IPI) P38063 (/IPI) P38063 (/IPI) P38063 (/IPI) P38620 (/IPI) P38620 (/IPI) P38620 (/IPI) P38620 (/IPI)
(15 more)
Pentose-phosphate shunt GO:0006098
The glucose-6-phosphate catabolic process in which, coupled to NADPH synthesis, glucose-6-P is oxidized with the formation of carbon dioxide (CO2) and ribulose 5-phosphate; ribulose 5-P then enters a series of reactions interconverting sugar phosphates. The pentose phosphate pathway is a major source of reducing equivalents for biosynthesis reactions and is also important for the conversion of hexoses to pentoses.
11 Q8IE67 (/ISS) Q8IE67 (/ISS) Q8IE67 (/ISS) Q8IE67 (/ISS) Q8IE67 (/ISS) Q8IE67 (/ISS) Q8IE67 (/ISS) Q8IE67 (/ISS) Q8IE67 (/ISS) Q8IE67 (/ISS)
(1 more)
Purine ribonucleoside salvage GO:0006166
Any process which produces a purine nucleoside from derivatives of it, without de novo synthesis.
11 Q8IE67 (/ISS) Q8IE67 (/ISS) Q8IE67 (/ISS) Q8IE67 (/ISS) Q8IE67 (/ISS) Q8IE67 (/ISS) Q8IE67 (/ISS) Q8IE67 (/ISS) Q8IE67 (/ISS) Q8IE67 (/ISS)
(1 more)
Regulation of cell size GO:0008361
Any process that modulates the size of a cell.
10 P38689 (/HMP) P38689 (/HMP) P38689 (/HMP) P38689 (/HMP) P38689 (/HMP) P38689 (/HMP) P38689 (/HMP) P38689 (/HMP) P38689 (/HMP) P38689 (/HMP)
Purine ribonucleotide biosynthetic process GO:0009152
The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
3 Q386K8 (/ISM) Q38A32 (/ISM) Q38A32 (/ISM)
Histidine biosynthetic process GO:0000105
The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
2 Q5ALK3 (/ISS) Q5ALK3 (/ISS)
Tryptophan biosynthetic process GO:0000162
The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate.
2 Q5ALK3 (/ISS) Q5ALK3 (/ISS)
5-phosphoribose 1-diphosphate biosynthetic process GO:0006015
The chemical reactions and pathways resulting in the formation of 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate.
2 O94413 (/ISO) P87171 (/ISO)
5-phosphoribose 1-diphosphate biosynthetic process GO:0006015
The chemical reactions and pathways resulting in the formation of 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate.
2 Q54PA9 (/ISS) Q75JN8 (/ISS)
'de novo' pyrimidine nucleobase biosynthetic process GO:0006207
The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases, beginning with the synthesis of a pyrimidine ring from simpler precursors.
2 Q5ALK3 (/ISS) Q5ALK3 (/ISS)
Histidine metabolic process GO:0006547
The chemical reactions and pathways involving histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
2 Q5BBW5 (/RCA) Q5BBW5 (/RCA)
Nucleoside metabolic process GO:0009116
The chemical reactions and pathways involving a nucleoside, a nucleobase linked to either beta-D-ribofuranose (a ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleoside), e.g. adenosine, guanosine, inosine, cytidine, uridine and deoxyadenosine, deoxyguanosine, deoxycytidine and thymidine (= deoxythymidine).
2 Q38A32 (/ISM) Q38A32 (/ISM)
NAD biosynthetic process GO:0009435
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
2 Q5ALK3 (/ISS) Q5ALK3 (/ISS)
Pyrimidine nucleobase biosynthetic process GO:0019856
The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases.
2 Q5ALK3 (/ISS) Q5ALK3 (/ISS)
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
2 Q5ALK3 (/IMP) Q5ALK3 (/IMP)
Purine-containing compound salvage GO:0043101
Any process that generates a purine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a purine base, from derivatives of them without de novo synthesis.
2 Q5ALK3 (/ISS) Q5ALK3 (/ISS)
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
1 Q54PA9 (/HEP)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
104 P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA) P0A717 (/IDA)
(94 more)
Ribose phosphate diphosphokinase complex GO:0002189
A protein complex having ribose phosphate diphosphokinase activity.
25 P38063 (/IDA) P38063 (/IDA) P38063 (/IDA) P38063 (/IDA) P38063 (/IDA) P38063 (/IDA) P38620 (/IDA) P38620 (/IDA) P38620 (/IDA) P38620 (/IDA)
(15 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
25 P38063 (/HDA) P38063 (/HDA) P38063 (/HDA) P38063 (/HDA) P38063 (/HDA) P38063 (/HDA) P38620 (/HDA) P38620 (/HDA) P38620 (/HDA) P38620 (/HDA)
(15 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
6 Q38A32 (/IDA) Q38A32 (/IDA) Q57ZX2 (/IDA) Q57ZX2 (/IDA) Q57ZX2 (/IDA) Q57ZX2 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 P87171 (/ISO) Q4Q0M2 (/ISO) Q4QI56 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O94413 (/HDA)
Glycosome GO:0020015
A membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis.
1 Q386K8 (/IDA)
Phagocytic vesicle GO:0045335
A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
1 Q54PA9 (/HDA)
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