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CATH Superfamily 3.40.50.2000

Glycogen Phosphorylase B;

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Glycogen Phosphorylase B;
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 40: UDP-glycosyltransferase 76C1

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D- glucosyltransferase. [EC: 2.4.1.202]
(1) UDP-alpha-D-glucose + 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin- 3(4H)-one = UDP + (2R)-4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4- benzoxazin-2-yl beta-D-glucopyranoside. (2) UDP-alpha-D-glucose + 2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one = UDP + (2R)-4-hydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D- glucopyranoside.
  • The enzyme is involved in the detoxification of the benzoxazinoids DIBOA (2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one) and DIMBOA (2,4- dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one) which are stored as the respective non-toxic glucosides in the vacuoles in some plants, most commonly from the family of Poaceae (grasses).
  • Benzoxazinoids are known to exhibit antimicrobial, antifeedant, and antiinsecticidal effects and are involved in the interaction of plants with other plants, insects, or microorganisms.
 5 A0A1R3M158 A0A1R3M158 B4G072 B4G072 Q8W2B7
7-deoxyloganetic acid glucosyltransferase. [EC: 2.4.1.323]
UDP-alpha-D-glucose + 7-deoxyloganetate = UDP + 7-deoxyloganate.
  • Isolated from the plant Catharanthus roseus (Madagascar periwinkle).
  • Involved in loganin and secologanin biosynthesis.
  • Does not react with 7-deoxyloganetin.
  • Cf. EC 2.4.1.324.
 5 U3U992 U5NDF6 U5NDF6 U5NH37 U5NH37
Flavonol 3-O-glucosyltransferase. [EC: 2.4.1.91]
UDP-glucose + a flavonol = UDP + a flavonol 3-O-D-glucoside.
  • Acts on a variety of flavonols, including quercetin and quercetin 7-O-glucoside.
  • Different from EC 2.4.1.81.
 4 Q94AB5 Q94AB5 W8QNL7 W8QNL7
Flavonol 7-O-beta-glucosyltransferase. [EC: 2.4.1.237]
UDP-glucose + a flavonol = UDP + a flavonol 7-O-beta-D-glucoside.
  • Acts on the flavonols gossypetin (8-hydroxyquercetin) and to a lesser extent on quercetin, kaempferol and myricetin.
 4 Q94AB5 Q94AB5 W8QNL7 W8QNL7
Abscisate beta-glucosyltransferase. [EC: 2.4.1.263]
UDP-D-glucose + abscisate = UDP + beta-D-glucopyranosyl abscisate.
  • The enzyme acts better on (S)-2-trans-abscisate than the natural (S)- 2-cis isomer, abscisate, or its enantiomer, the (R)-2-cis isomer.
 1 K4D3V7
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