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CATH Superfamily 3.40.50.2000

Glycogen Phosphorylase B;

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Glycogen Phosphorylase B;
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 265: D-inositol 3-phosphate glycosyltransferase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
D-inositol-3-phosphate glycosyltransferase. [EC: 2.4.1.250]
UDP-N-acetyl-D-glucosamine + 1D-myo-inositol 3-phosphate = UDP + 1-O- (2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol 3-phosphate.
  • The enzyme, which belongs to the GT-B fold superfamily, catalyzes the first dedicated reaction in the biosynthesis of mycothiol.
  • The substrate was initially believed to be inositol, but eventually shown to be D-myo-inositol 3-phosphate.
  • A substantial conformational change occurs upon UDP binding, which generates the binding site for D-myo-inositol 3-phosphate.
  • Formerly EC 2.4.1.n3.
 100 A0A045H6I5 A0A045H6I5 A0A045H6I5 A0A045H6I5 A0A045H6I5 A0A045H6I5 A0A045H6I5 A0A045H6I5 A0A045H6I5 A0A045H6I5
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