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CATH Superfamily 3.40.50.2000

Glycogen Phosphorylase B;

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Glycogen Phosphorylase B;
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 261: Putative glycosyl transferase

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
3-alpha-mycarosylerythronolide B desosaminyl transferase. [EC: 2.4.1.278]
dTDP-D-desosamine + 3-alpha-L-mycarosylerythronolide B = dTDP + erythromycin D.
  • The enzyme is involved in erythromycin biosynthesis.
 4 A0A2A9J4E4 A0A2A9J4E4 A4F7P3 A4F7P3
8-demethyltetracenomycin C L-rhamnosyltransferase. [EC: 2.4.1.331]
dTDP-beta-L-rhamnose + 8-demethyltetracenomycin C = dTDP + 8-demethyl-8- alpha-L-rhamnosyltetracenomycin C.
  • Isolated from Streptomyces olivaceus Tu2353.
  • Involved in elloramycin biosynthesis.
  • In vitro it can also utilize other 6-deoxy D- or L-hexoses.
 1 Q9F2F9
L-demethylnoviosyl transferase. [EC: 2.4.1.302]
dTDP-4-O-demethyl-beta-L-noviose + novobiocic acid = dTDP + demethyldecarbamoyl novobiocin.
  • The enzyme is involved in the biosynthesis of the aminocoumarin antibiotic, novobiocin.
 1 Q9L9F5
10-deoxymethynolide desosaminyltransferase. [EC: 2.4.1.277]
dTDP-3-dimethylamino-3,4,6-trideoxy-alpha-D-glucopyranose + 10-deoxymethynolide = dTDP + 10-deoxymethymycin.
  • DesVII is the glycosyltransferase responsible for the attachment of dTDP-D-desosamine to 10-deoxymethynolide or narbonolide during the biosynthesis of methymycin, neomethymycin, narbomycin, and pikromycin in the bacterium Streptomyces venezuelae.
  • Activity requires an additional protein partner, DesVIII.
 1 Q9ZGH7
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