The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Peptidase S8/S53 domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 18: Type VII secretion-associated serine protease myco...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Serine-type endopeptidase activity GO:0004252
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
5 O05461 (/IDA) O05461 (/IDA) O05461 (/IDA) O05461 (/IDA) O05461 (/IDA)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
5 O05461 (/IDA) O05461 (/IDA) O05461 (/IDA) O05461 (/IDA) O05461 (/IDA)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
5 O05461 (/IDA) O05461 (/IDA) O05461 (/IDA) O05461 (/IDA) O05461 (/IDA)
Regulation of secretion GO:0051046
Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.
5 O05461 (/IDA) O05461 (/IDA) O05461 (/IDA) O05461 (/IDA) O05461 (/IDA)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
20 O05458 (/IDA) O05458 (/IDA) O05458 (/IDA) O05458 (/IDA) O05458 (/IDA) O05458 (/IDA) O05458 (/IDA) O05461 (/IDA) O05461 (/IDA) O05461 (/IDA)
(10 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
15 O05458 (/HDA) O05458 (/HDA) O05458 (/HDA) O05458 (/HDA) O05458 (/HDA) O05458 (/HDA) O05458 (/HDA) O53695 (/HDA) O53695 (/HDA) O53695 (/HDA)
(5 more)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
8 O53695 (/HDA) O53695 (/HDA) O53695 (/HDA) O53695 (/HDA) O53695 (/HDA) O53695 (/HDA) O53695 (/HDA) O53695 (/HDA)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
8 O53695 (/HDA) O53695 (/HDA) O53695 (/HDA) O53695 (/HDA) O53695 (/HDA) O53695 (/HDA) O53695 (/HDA) O53695 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
8 O06316 (/HDA) O06316 (/HDA) O06316 (/HDA) O06316 (/HDA) O06316 (/HDA) O06316 (/HDA) O06316 (/HDA) O06316 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
8 O53695 (/HDA) O53695 (/HDA) O53695 (/HDA) O53695 (/HDA) O53695 (/HDA) O53695 (/HDA) O53695 (/HDA) O53695 (/HDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
5 O05461 (/IDA) O05461 (/IDA) O05461 (/IDA) O05461 (/IDA) O05461 (/IDA)