The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 7: Pentafunctional AROM polypeptide

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
3-dehydroquinate synthase. [EC: 4.2.3.4]
3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate.
  • The hydrogen atoms on C-7 of the substrate are retained on C-2 of the products.
  • Formerly EC 4.6.1.3.
212 A0A098MG32 A0A098MG32 A0A098MG32 A0A098MG32 A0A098MG32 A0A098MG32 A0A098MG32 A0A098MG32 A0A098MG32 A0A098MG32
(202 more...)
Shikimate kinase. [EC: 2.7.1.71]
ATP + shikimate = ADP + shikimate 3-phosphate.
    44 A0A0B0DHB1 A0A0B0DHB1 A0A1D9QLW8 A0A1D9QLW8 A0A1H6PWB9 A0A1H6PWB9 A0A3M7K8K1 A0A3M7K8K1 A0A3M7K8K1 A1CP85
    (34 more...)
    3-phosphoshikimate 1-carboxyvinyltransferase. [EC: 2.5.1.19]
    Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O- (1-carboxyvinyl)-3-phosphoshikimate.
      44 A0A0B0DHB1 A0A0B0DHB1 A0A1D9QLW8 A0A1D9QLW8 A0A1H6PWB9 A0A1H6PWB9 A0A3M7K8K1 A0A3M7K8K1 A0A3M7K8K1 A1CP85
      (34 more...)
      Shikimate dehydrogenase. [EC: 1.1.1.25]
      Shikimate + NADP(+) = 3-dehydroshikimate + NADPH.
      • NAD(+) cannot replace NADP(+).
      • In higher organisms, this enzyme forms part of a multienzyme complex with EC 4.2.1.10.
      44 A0A0B0DHB1 A0A0B0DHB1 A0A1D9QLW8 A0A1D9QLW8 A0A1H6PWB9 A0A1H6PWB9 A0A3M7K8K1 A0A3M7K8K1 A0A3M7K8K1 A1CP85
      (34 more...)
      3-dehydroquinate dehydratase. [EC: 4.2.1.10]
      3-dehydroquinate = 3-dehydroshikimate + H(2)O.
        44 A0A0B0DHB1 A0A0B0DHB1 A0A1D9QLW8 A0A1D9QLW8 A0A1H6PWB9 A0A1H6PWB9 A0A3M7K8K1 A0A3M7K8K1 A0A3M7K8K1 A1CP85
        (34 more...)
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