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CATH Superfamily 3.40.50.1970

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 45: Aldehyde-alcohol dehydrogenase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Alcohol dehydrogenase. [EC: 1.1.1.1]
(1) A primary alcohol + NAD(+) = an aldehyde + NADH. (2) A secondary alcohol + NAD(+) = a ketone + NADH.
  • Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.
  • The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.
 9 A0A0K2A0G4 A0A0K2A0G4 A0A0K2A0G4 A0A2P8MA19 A0A2P8MA19 A0A2P8MA19 P33744 P33744 P33744
Aldehyde dehydrogenase (NAD(+)). [EC: 1.2.1.3]
An aldehyde + NAD(+) + H(2)O = a carboxylate + NADH.
  • Wide specificity, including oxidation of D-glucuronolactone to D-glucarate.
  • Formerly EC 1.1.1.70.
 9 A0A0K2A0G4 A0A0K2A0G4 A0A0K2A0G4 A0A2P8MA19 A0A2P8MA19 A0A2P8MA19 P33744 P33744 P33744