The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 10: Probable hydroxyacid-oxoacid transhydrogenase, mit...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Hydroxyacid-oxoacid transhydrogenase activity GO:0047988
Catalysis of the reaction: (S)-3-hydroxybutanoate + 2-oxoglutarate = acetoacetate + (R)-2-hydroxyglutarate.
11 A6QP15 (/ISS) Q08B39 (/ISS) Q17EN4 (/ISS) Q28XT3 (/ISS) Q28XT3 (/ISS) Q4QQW3 (/ISS) Q5RF11 (/ISS) Q6P371 (/ISS) Q7Q547 (/ISS) Q8R0N6 (/ISS)
(1 more)
Hydroxyacid-oxoacid transhydrogenase activity GO:0047988
Catalysis of the reaction: (S)-3-hydroxybutanoate + 2-oxoglutarate = acetoacetate + (R)-2-hydroxyglutarate.
1 Q8IWW8 (/EXP)
Hydroxyacid-oxoacid transhydrogenase activity GO:0047988
Catalysis of the reaction: (S)-3-hydroxybutanoate + 2-oxoglutarate = acetoacetate + (R)-2-hydroxyglutarate.
1 Q8IWW8 (/IDA)
Hydroxyacid-oxoacid transhydrogenase activity GO:0047988
Catalysis of the reaction: (S)-3-hydroxybutanoate + 2-oxoglutarate = acetoacetate + (R)-2-hydroxyglutarate.
1 Q8R0N6 (/ISO)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glutamate catabolic process via 2-oxoglutarate GO:0006539
The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxoglutarate.
11 A6QP15 (/ISS) Q08B39 (/ISS) Q17EN4 (/ISS) Q28XT3 (/ISS) Q28XT3 (/ISS) Q4QQW3 (/ISS) Q5RF11 (/ISS) Q6P371 (/ISS) Q7Q547 (/ISS) Q8R0N6 (/ISS)
(1 more)
2-oxoglutarate metabolic process GO:0006103
The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism.
1 Q8IWW8 (/TAS)
Glutamate catabolic process via 2-oxoglutarate GO:0006539
The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxoglutarate.
1 Q8IWW8 (/IDA)
Glutamate catabolic process via 2-oxoglutarate GO:0006539
The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxoglutarate.
1 Q8R0N6 (/ISO)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
11 A6QP15 (/ISS) Q08B39 (/ISS) Q17EN4 (/ISS) Q28XT3 (/ISS) Q28XT3 (/ISS) Q4QQW3 (/ISS) Q5RF11 (/ISS) Q6P371 (/ISS) Q7Q547 (/ISS) Q8IWW8 (/ISS)
(1 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q8R0N6 (/IDA)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
1 Q8IWW8 (/TAS)
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