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CATH Superfamily 3.40.50.1820

Alpha/Beta hydrolase fold, catalytic domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
alpha/beta hydrolase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 35: Acetyl esterase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Acetylesterase activity GO:0008126
Catalysis of the reaction: an acetic ester + H2O = an alcohol + acetate.
 46 C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA)
(36 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 23 P23872 (/IPI) P23872 (/IPI) P23872 (/IPI) P23872 (/IPI) P23872 (/IPI) P23872 (/IPI) P23872 (/IPI) P23872 (/IPI) P23872 (/IPI) P23872 (/IPI)
(13 more)
Hydrolase activity GO:0016787
Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
 23 P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA)
(13 more)
Short-chain carboxylesterase activity GO:0034338
Catalysis of the reaction: a carboxylic ester + H2O = an alcohol + a carboxylic anion, where the carboxylic chain has 8 or fewer carbon atoms.
 23 P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA)
(13 more)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of DNA-binding transcription factor activity GO:0043433
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
 23 P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA)
(13 more)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
 23 C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA)
(13 more)
Negative regulation of hydrolase activity GO:0051346
Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.
 23 P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA) P23872 (/IDA)
(13 more)
Negative regulation of maltose transport GO:1902344
Any process that stops, prevents or reduces the frequency, rate or extent of maltose transport.
 23 C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA)
(13 more)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
 23 C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA) C4ZUT0 (/IDA)
(13 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
 23 P23872 (/NAS) P23872 (/NAS) P23872 (/NAS) P23872 (/NAS) P23872 (/NAS) P23872 (/NAS) P23872 (/NAS) P23872 (/NAS) P23872 (/NAS) P23872 (/NAS)
(13 more)