View in Gene3D

CATH Superfamily 3.40.50.1580

Nucleoside phosphorylase domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Nucleoside phosphorylase domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 26: Aminodeoxyfutalosine nucleosidase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Adenosylhomocysteine nucleosidase. [EC: 3.2.2.9]
S-adenosyl-L-homocysteine + H(2)O = S-(5-deoxy-D-ribos-5-yl)-L- homocysteine + adenine.
    		 5 A0A2J9KKR3 A0A2J9KKR3 O24915 O24915 Q9ZMY2
    Aminodeoxyfutalosine nucleosidase. [EC: 3.2.2.30]
    6-amino-6-deoxyfutalosine + H(2)O = dehypoxanthine futalosine + adenine.
    • The enzyme, found in several bacterial species, catalyzes a step in a modified futalosine pathway for menaquinone biosynthesis.
    • While the enzyme from some organisms also has the activity of EC 3.2.2.9 the enzyme from Chlamydia trachomatis is specific for 6-amino-6-deoxyfutalosine.
    		 5 A0A2J9KKR3 A0A2J9KKR3 O24915 O24915 Q9ZMY2
    CATH-Gene3D is a Global Biodata Core Resource Learn more...