The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 92: Leucine carboxyl methyltransferase 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein C-terminal carboxyl O-methyltransferase activity GO:0003880
Catalysis of the transfer of a methyl group to the oxygen atom of a carboxyl group at the C-terminal of a protein.
3 Q9UIC8 (/IDA) Q9UIC8 (/IDA) Q9UIC8 (/IDA)
Protein C-terminal carboxyl O-methyltransferase activity GO:0003880
Catalysis of the transfer of a methyl group to the oxygen atom of a carboxyl group at the C-terminal of a protein.
3 A0A0U1RNF2 (/ISO) A2RTH5 (/ISO) O94257 (/ISO)
Protein C-terminal carboxyl O-methyltransferase activity GO:0003880
Catalysis of the transfer of a methyl group to the oxygen atom of a carboxyl group at the C-terminal of a protein.
3 Q9UIC8 (/TAS) Q9UIC8 (/TAS) Q9UIC8 (/TAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 Q9UIC8 (/IPI) Q9UIC8 (/IPI) Q9UIC8 (/IPI)
S-adenosylmethionine-dependent methyltransferase activity GO:0008757
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.
3 Q9UIC8 (/TAS) Q9UIC8 (/TAS) Q9UIC8 (/TAS)
Protein C-terminal leucine carboxyl O-methyltransferase activity GO:0018423
Catalysis of the reaction: S-adenosyl-L-methionine + protein L-leucine = S-adenosyl-L-homocysteine + protein L-leucine methyl ester. This modification occurs only at the oxygen atoms of the free alpha carboxyl group of a leucine residue at the C-terminus of the protein.
3 Q9UIC8 (/TAS) Q9UIC8 (/TAS) Q9UIC8 (/TAS)
Protein methyltransferase activity GO:0008276
Catalysis of the transfer of a methyl group (CH3-) to a protein.
2 A0A0U1RNF2 (/IDA) A2RTH5 (/IDA)
S-adenosylmethionine-dependent methyltransferase activity GO:0008757
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.
1 Q8VY08 (/IDA)

There are 16 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein methylation GO:0006479
The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.
5 A0A0U1RNF2 (/IMP) A2RTH5 (/IMP) Q9UIC8 (/IMP) Q9UIC8 (/IMP) Q9UIC8 (/IMP)
G2/M transition of mitotic cell cycle GO:0000086
The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
3 Q9UIC8 (/TAS) Q9UIC8 (/TAS) Q9UIC8 (/TAS)
Cellular protein modification process GO:0006464
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
3 Q9UIC8 (/TAS) Q9UIC8 (/TAS) Q9UIC8 (/TAS)
C-terminal protein methylation GO:0006481
The methylation of the C-terminal amino acid of a protein.
3 Q9UIC8 (/IDA) Q9UIC8 (/IDA) Q9UIC8 (/IDA)
C-terminal protein methylation GO:0006481
The methylation of the C-terminal amino acid of a protein.
3 A0A0U1RNF2 (/ISO) A2RTH5 (/ISO) O94257 (/ISO)
Negative regulation of protein complex assembly GO:0031333
Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly.
3 Q9UIC8 (/IMP) Q9UIC8 (/IMP) Q9UIC8 (/IMP)
Regulation of apoptotic process GO:0042981
Any process that modulates the occurrence or rate of cell death by apoptotic process.
3 Q9UIC8 (/IMP) Q9UIC8 (/IMP) Q9UIC8 (/IMP)
Regulation of mitotic cell cycle spindle assembly checkpoint GO:0090266
Any process that modulates the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.
3 Q9UIC8 (/IMP) Q9UIC8 (/IMP) Q9UIC8 (/IMP)
Protein methylation GO:0006479
The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.
2 A0A0U1RNF2 (/ISO) A2RTH5 (/ISO)
Regulation of glucose metabolic process GO:0010906
Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.
2 A0A0U1RNF2 (/IMP) A2RTH5 (/IMP)
Negative regulation of protein complex assembly GO:0031333
Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly.
2 A0A0U1RNF2 (/ISO) A2RTH5 (/ISO)
Regulation of apoptotic process GO:0042981
Any process that modulates the occurrence or rate of cell death by apoptotic process.
2 A0A0U1RNF2 (/ISO) A2RTH5 (/ISO)
Regulation of mitotic cell cycle spindle assembly checkpoint GO:0090266
Any process that modulates the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.
2 A0A0U1RNF2 (/ISO) A2RTH5 (/ISO)
Regulation of autophagy GO:0010506
Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
1 O94257 (/ISO)
Methylation GO:0032259
The process in which a methyl group is covalently attached to a molecule.
1 Q8VY08 (/IDA)
Negative regulation of brassinosteroid mediated signaling pathway GO:1900458
Any process that stops, prevents or reduces the frequency, rate or extent of brassinosteroid mediated signaling pathway.
1 Q8VY08 (/IDA)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
3 Q9UIC8 (/TAS) Q9UIC8 (/TAS) Q9UIC8 (/TAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 A0A0U1RNF2 (/IDA) A2RTH5 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q8VY08 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 O94257 (/HDA)
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