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CATH Superfamily 3.40.50.150

Vaccinia Virus protein VP39

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 769: Precorrin-6Y C(5,15)-methyltransferase [decarboxyl...

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Precorrin-6B C(5,15)-methyltransferase (decarboxylating). [EC: 2.1.1.132]
2 S-adenosyl-L-methionine + precorrin-6B = 2 S-adenosyl-L-homocysteine + precorrin-8X + CO(2).
  • The enzyme, which participates in the aerobic adenosylcobalamin biosynthesis pathway, has S-adenosyl-L-methionine-dependent methyltransferase and decarboxylase activities.
  • The enzyme is a fusion protein with two active sites; one catalyzes the methylation at C(15) and the decarboxylation, while the other catalyzes the methylation at C(5).
 10 A0A0T9BPM6 A0A0T9BPM6 A0A0T9BPM6 A5U497 A5U497 A5U497 P9WGA8 P9WGA9 P9WGA9 P9WGA9
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