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CATH Superfamily 3.40.50.150

Vaccinia Virus protein VP39

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 65: Phenylethanolamine N-methyltransferase

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phenylethanolamine N-methyltransferase. [EC: 2.1.1.28]
S-adenosyl-L-methionine + phenylethanolamine = S-adenosyl-L-homocysteine + N-methylphenylethanolamine.
  • Acts on various phenylethanolamines; converts noradrenaline into adrenaline.
 11 A0A480QS50 A0A480QS50 P10937 P10938 P11086 P40935 P40935 Q06AU9 Q06AU9 Q0VB50
(1 more...)
Nicotinamide N-methyltransferase. [EC: 2.1.1.1]
S-adenosyl-L-methionine + nicotinamide = S-adenosyl-L-homocysteine + 1-methylnicotinamide.
    		 6 O55239 P40261 P40261 Q06AV1 Q6FH49 Q6FH49
    Amine N-methyltransferase. [EC: 2.1.1.49]
    S-adenosyl-L-methionine + an amine = S-adenosyl-L-homocysteine + a methylated amine.
    • An enzyme of very broad specificity; many primary, secondary and tertiary amines can act as acceptors, including tryptamine, aniline, nicotine and a variety of drugs and other xenobiotics.
    • Formerly EC 2.1.1.81.
    		 4 O95050 O97972 P40936 Q5RFR7
    Thioether S-methyltransferase. [EC: 2.1.1.96]
    S-adenosyl-L-methionine + dimethyl sulfide = S-adenosyl-L-homocysteine + trimethylsulfonium.
    • Also acts on dimethyl selenide, dimethyl telluride, diethyl sulfide, 1,4-dithiane and many other thioethers.
    		 4 O95050 O97972 P40936 Q5RFR7
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