The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 61: Caffeic acid O-methyltransferase

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Caffeate O-methyltransferase. [EC: 2.1.1.68]
S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L- homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate.
  • 3,4-dihydroxybenzaldehyde and catechol can act as acceptor, more slowly.
15 A0A0E0QEJ7 A0A0E0QEJ7 O82054 P28002 Q00763 Q06509 Q06509 Q41086 Q43046 Q43047
(5 more...)
Flavone 3'-O-methyltransferase. [EC: 2.1.1.42]
S-adenosyl-L-methionine + 3'-hydroxyflavone = S-adenosyl-L-homocysteine + 3'-methoxyflavone.
  • The enzyme prefers flavones with vicinal 3',4'-dihydroxyl groups.
5 A0A0E0QEJ7 A0A0E0QEJ7 Q6ZD89 Q6ZD89 Q9FK25
Acetylserotonin O-methyltransferase. [EC: 2.1.1.4]
S-adenosyl-L-methionine + N-acetylserotonin = S-adenosyl-L-homocysteine + melatonin.
  • Some other hydroxyindoles also act as acceptor, more slowly.
5 A0A0E0QEJ7 A0A0E0QEJ7 Q6ZD89 Q6ZD89 Q9FK25
(Iso)eugenol O-methyltransferase. [EC: 2.1.1.146]
S-adenosyl-L-methionine + isoeugenol = S-adenosyl-L-homocysteine + isomethyleugenol.
  • Acts on eugenol and chavicol as well as isoeugenol.
4 A0A1B6PFT6 A0A1B6PFT6 A8QW52 A8QW52
Naringenin 7-O-methyltransferase. [EC: 2.1.1.232]
S-adenosyl-L-methionine + (2S)-naringenin = S-adenosyl-L-homocysteine + (2S)-sakuranetin.
  • The enzyme is involved in the biosynthesis of the sakuranetin, an inducible defense mechanism of Oryza sativa against pathogen attack.
1 Q0IP69
CATH-Gene3D is a Global Biodata Core Resource Learn more...