The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 59: spermine synthase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Spermine synthase activity GO:0016768
Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + spermine.
6 P52788 (/TAS) P52788 (/TAS) P52788 (/TAS) P52788 (/TAS) P52788 (/TAS) P52788 (/TAS)
Spermine synthase activity GO:0016768
Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + spermine.
1 Q3MIE9 (/IMP)
Spermine synthase activity GO:0016768
Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + spermine.
1 P97355 (/ISO)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Methionine metabolic process GO:0006555
The chemical reactions and pathways involving methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
6 P52788 (/TAS) P52788 (/TAS) P52788 (/TAS) P52788 (/TAS) P52788 (/TAS) P52788 (/TAS)
Polyamine metabolic process GO:0006595
The chemical reactions and pathways involving polyamines, any organic compound containing two or more amino groups.
6 P52788 (/TAS) P52788 (/TAS) P52788 (/TAS) P52788 (/TAS) P52788 (/TAS) P52788 (/TAS)
Spermine biosynthetic process GO:0006597
The chemical reactions and pathways resulting in the formation of spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses and involved in nucleic acid packaging.
1 Q3MIE9 (/IMP)
Spermine biosynthetic process GO:0006597
The chemical reactions and pathways resulting in the formation of spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses and involved in nucleic acid packaging.
1 P97355 (/ISO)
Spermine metabolic process GO:0008215
The chemical reactions and pathways involving spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication.
1 P97355 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
6 P52788 (/TAS) P52788 (/TAS) P52788 (/TAS) P52788 (/TAS) P52788 (/TAS) P52788 (/TAS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
6 P52788 (/HDA) P52788 (/HDA) P52788 (/HDA) P52788 (/HDA) P52788 (/HDA) P52788 (/HDA)
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