The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Vaccinia Virus protein VP39
".
FunFam 52: Probable histone-arginine methyltransferase CARM1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 10 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Histone methyltransferase activity GO:0042054
Catalysis of the reaction: S-adenosyl-L-methionine + histone = S-adenosyl-L-homocysteine + methyl-histone. Histone methylation generally occurs on either an arginine or lysine residue.
|
7 | A2YPT7 (/ISS) A2YPT7 (/ISS) B0W3L6 (/ISS) Q174R2 (/ISS) Q7Q2B7 (/ISS) Q7XI75 (/ISS) Q7XI75 (/ISS) |
|
Protein-arginine omega-N monomethyltransferase activity GO:0035241
Catalysis of the addition of a methyl group to either of the unmethylated terminal nitrogen atoms (also called omega nitrogen) in peptidyl-arginine to form an omega-N-G-monomethylated arginine residue. The reaction is S-adenosyl-L-methionine +
|
3 | A3KPF2 (/IDA) Q7Q2B7 (/IDA) Q84W92 (/IDA) |
|
Protein-arginine omega-N asymmetric methyltransferase activity GO:0035242
Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the same terminal nitrogen (omega nitrogen) residue that was previously methylated, resulting in asymmetrical peptidyl-N(omega),N(omega)-dimethylated arginine residues.
|
3 | A3KPF2 (/IDA) Q7Q2B7 (/IDA) Q84W92 (/IDA) |
|
Histone-arginine N-methyltransferase activity GO:0008469
Catalysis of the reaction: S-adenosyl-L-methionine + (histone)-arginine = S-adenosyl-L-homocysteine + (histone)-N-methyl-arginine.
|
2 | A3KPF2 (/IDA) Q84W92 (/IDA) |
|
[myelin basic protein]-arginine N-methyltransferase activity GO:0016277
Catalysis of the reaction: S-adenosyl-L-methionine + (myelin basic protein)-arginine = S-adenosyl-L-homocysteine + (myelin basic protein)-N(omega)-methyl-arginine.
|
2 | A3KPF2 (/IDA) Q84W92 (/IDA) |
|
Protein-arginine omega-N monomethyltransferase activity GO:0035241
Catalysis of the addition of a methyl group to either of the unmethylated terminal nitrogen atoms (also called omega nitrogen) in peptidyl-arginine to form an omega-N-G-monomethylated arginine residue. The reaction is S-adenosyl-L-methionine +
|
2 | B0W3L6 (/ISS) Q174R2 (/ISS) |
|
Protein-arginine omega-N asymmetric methyltransferase activity GO:0035242
Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the same terminal nitrogen (omega nitrogen) residue that was previously methylated, resulting in asymmetrical peptidyl-N(omega),N(omega)-dimethylated arginine residues.
|
2 | B0W3L6 (/ISS) Q174R2 (/ISS) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
2 | A3KPF2 (/IPI) Q84W92 (/IPI) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
2 | A3KPF2 (/IPI) Q84W92 (/IPI) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q84W92 (/IPI) |
There are 17 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Histone arginine methylation GO:0034969
The modification of a histone by addition of a methyl group to an arginine residue.
|
7 | A2YPT7 (/ISS) A2YPT7 (/ISS) B0W3L6 (/ISS) Q174R2 (/ISS) Q7Q2B7 (/ISS) Q7XI75 (/ISS) Q7XI75 (/ISS) |
|
Peptidyl-arginine methylation, to asymmetrical-dimethyl arginine GO:0019919
The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N(omega)-dimethyl-L-arginine.
|
3 | A3KPF2 (/IDA) Q7Q2B7 (/IDA) Q84W92 (/IDA) |
|
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
|
2 | B0W3L6 (/ISS) Q174R2 (/ISS) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | B0W3L6 (/ISS) Q174R2 (/ISS) |
|
Regulation of flower development GO:0009909
Any process that modulates the frequency, rate or extent of flower development.
|
2 | A3KPF2 (/IGI) Q84W92 (/IGI) |
|
Vegetative to reproductive phase transition of meristem GO:0010228
The process involved in transforming a meristem that produces vegetative structures, such as leaves, into a meristem that produces reproductive structures, such as a flower or an inflorescence.
|
2 | A3KPF2 (/IGI) Q84W92 (/IGI) |
|
Peptidyl-arginine methylation, to asymmetrical-dimethyl arginine GO:0019919
The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N(omega)-dimethyl-L-arginine.
|
2 | B0W3L6 (/ISS) Q174R2 (/ISS) |
|
Histone H3-R2 methylation GO:0034970
The modification of histone H3 by addition of a methyl group to arginine at position 2 of the histone.
|
2 | A3KPF2 (/IDA) Q84W92 (/IDA) |
|
Histone H3-R17 methylation GO:0034971
The modification of histone H3 by addition of a methyl group to arginine at position 17 of the histone.
|
2 | A3KPF2 (/IGI) Q84W92 (/IGI) |
|
Histone H3-R26 methylation GO:0034972
The modification of histone H3 by addition of a methyl group to arginine at position 26 of the histone.
|
2 | A3KPF2 (/IDA) Q84W92 (/IDA) |
|
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
|
1 | Q7Q2B7 (/IDA) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q7Q2B7 (/IDA) |
|
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
|
1 | Q84W92 (/IMP) |
|
Histone H3-R17 methylation GO:0034971
The modification of histone H3 by addition of a methyl group to arginine at position 17 of the histone.
|
1 | Q84W92 (/IMP) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q84W92 (/IMP) |
|
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
|
1 | Q84W92 (/IMP) |
|
Positive regulation of response to oxidative stress GO:1902884
Any process that activates or increases the frequency, rate or extent of response to oxidative stress.
|
1 | Q84W92 (/IMP) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | B0W3L6 (/ISS) Q174R2 (/ISS) Q7Q2B7 (/ISS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
3 | B0W3L6 (/ISS) Q174R2 (/ISS) Q7Q2B7 (/ISS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | A3KPF2 (/IDA) Q84W92 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | A3KPF2 (/IDA) Q84W92 (/IDA) |
