CATH Superfamily 3.40.50.150

FunFam 341: Ribosomal RNA large subunit methyltransferase K/L

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term	Annotations	Evidence
23S rRNA (guanine(2445)-N(2))-methyltransferase. [EC: 2.1.1.173] S-adenosyl-L-methionine + guanine(2445) in 23S rRNA = S-adenosyl-L- homocysteine + N(2)-methylguanine(2445) in 23S rRNA. The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate. The enzyme specifically methylates guanine(2445) at N(2) in 23S rRNA. Formerly EC 2.1.1.52.	32	A0A0U4VJK8 A0A0U4VJK8 A0A0U4VJK8 A0A0U5BRP8 A0A0U5BRP8 A0A0U5BRP8 A0A0U5BRP8 A0A1T1S532 A0A1T1S532 A0A1T1S532 (22 more...)
23S rRNA (guanine(2069)-N(7))-methyltransferase. [EC: 2.1.1.264] S-adenosyl-L-methionine + guanine(2069) in 23S rRNA = S-adenosyl-L- homocysteine + N(7)-methylguanine(2069) in 23S rRNA. The enzyme specifically methylates guanine(2069) at position N7 in 23S rRNA. In gamma-proteobacteria the enzyme also catalyzes EC 2.1.1.173, while in beta-proteobacteria the activities are carried out by separate proteins. The enzyme from the gamma-proteobacterium Escherichia coli has RNA unwinding activity as well.	32	A0A0U4VJK8 A0A0U4VJK8 A0A0U4VJK8 A0A0U5BRP8 A0A0U5BRP8 A0A0U5BRP8 A0A0U5BRP8 A0A1T1S532 A0A1T1S532 A0A1T1S532 (22 more...)

CATH Superfamily 3.40.50.150

Vaccinia Virus protein VP39

Functional Families

FunFam 341: Ribosomal RNA large subunit methyltransferase K/L

There are 2 EC terms in this cluster