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CATH Superfamily 3.40.50.150

Vaccinia Virus protein VP39

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 331: Macrocin O-methyltransferase

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
8-demethyl-8-(2,3-dimethoxy-alpha-L-rhamnosyl)-tetracenomycin-C 4'-O- methyltransferase. [EC: 2.1.1.307]
S-adenosyl-L-methionine + 8-demethyl-8-(2,3-di-O-methyl-alpha-L- rhamnosyl)-tetracenomycin C = S-adenosyl-L-homocysteine + 8-demethyl-8- (2,3,4-tri-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C.
  • The enzyme from the bacterium Streptomyces olivaceus is involved in the biosynthesis of the polyketide elloramycin.
 1 Q9AJU0
Mycinamicin III 3''-O-methyltransferase. [EC: 2.1.1.237]
S-adenosyl-L-methionine + mycinamicin III = S-adenosyl-L-homocysteine + mycinamicin IV.
  • The enzyme is involved in the biosynthesis of mycinamicin macrolide antibiotics.
 1 Q49492
Demethyldecarbamoylnovobiocin O-methyltransferase. [EC: 2.1.1.285]
S-adenosyl-L-methionine + demethyldecarbamoylnovobiocin = S-adenosyl-L- homocysteine + decarbamoylnovobiocin.
  • The enzyme is involved in the biosynthesis of the aminocoumarin antibiotic novobiocin.
 1 Q9L9F2
Macrocin O-methyltransferase. [EC: 2.1.1.101]
S-adenosyl-L-methionine + macrocin = S-adenosyl-L-homocysteine + tylosin.
  • The 3-hydroxyl group of a 2-O-methyl-6-deoxy-D-allose residue in the macrolide antibiotic macrocin acts as methyl acceptor.
  • Isolated from Streptomyces fradiae.
  • Tylosin is a macrolide antibiotic.
  • Not identical with EC 2.1.1.102.
 1 Q9S4D5