The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 188: Protein-lysine methyltransferase METTL21C

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein-lysine N-methyltransferase activity GO:0016279
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate.
3 A6QP81 (/ISS) Q8BLU2 (/ISS) Q8BLU2 (/ISS)
Protein-lysine N-methyltransferase activity GO:0016279
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate.
2 Q8BLU2 (/ISO) Q8BLU2 (/ISO)
Heat shock protein binding GO:0031072
Interacting selectively and non-covalently with a heat shock protein, any protein synthesized or activated in response to heat shock.
2 Q8BLU2 (/ISO) Q8BLU2 (/ISO)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q5VZV1 (/IPI)
Protein-lysine N-methyltransferase activity GO:0016279
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate.
1 Q5VZV1 (/IDA)
Heat shock protein binding GO:0031072
Interacting selectively and non-covalently with a heat shock protein, any protein synthesized or activated in response to heat shock.
1 Q5VZV1 (/IPI)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein methylation GO:0006479
The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.
3 A6QP81 (/ISS) Q8BLU2 (/ISS) Q8BLU2 (/ISS)
Protein methylation GO:0006479
The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.
2 Q8BLU2 (/ISO) Q8BLU2 (/ISO)
Skeletal muscle tissue development GO:0007519
The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers.
2 Q8BLU2 (/IMP) Q8BLU2 (/IMP)
Hormone-mediated apoptotic signaling pathway GO:0008628
A series of molecular signals mediated by the detection of a hormone, and which triggers the apoptotic signaling pathway in a cell. The pathway starts with reception of a hormone signal, and ends when the execution phase of apoptosis is triggered.
2 Q8BLU2 (/IMP) Q8BLU2 (/IMP)
Regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880
Any process that modulates the rate, frequency or extent of release of sequestered calcium ion into cytosol by the sarcoplasmic reticulum, the process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.
2 Q8BLU2 (/IMP) Q8BLU2 (/IMP)
Cellular response to dexamethasone stimulus GO:0071549
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus.
2 Q8BLU2 (/IMP) Q8BLU2 (/IMP)
Protein methylation GO:0006479
The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.
1 Q5VZV1 (/IDA)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q8BLU2 (/ISO) Q8BLU2 (/ISO)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
2 Q8BLU2 (/ISO) Q8BLU2 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q5VZV1 (/IDA)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 Q5VZV1 (/IDA)
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