The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 17: probable 18S rRNA (Guanine-N(7))-methyltransferase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RRNA (guanine) methyltransferase activity GO:0016435
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylguanine.
9 O43709 (/IMP) O43709 (/IMP) P25627 (/IMP) P25627 (/IMP) P25627 (/IMP) P25627 (/IMP) P25627 (/IMP) P25627 (/IMP) P25627 (/IMP)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
7 P25627 (/IPI) P25627 (/IPI) P25627 (/IPI) P25627 (/IPI) P25627 (/IPI) P25627 (/IPI) P25627 (/IPI)
S-adenosylmethionine-dependent methyltransferase activity GO:0008757
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.
7 P25627 (/ISS) P25627 (/ISS) P25627 (/ISS) P25627 (/ISS) P25627 (/ISS) P25627 (/ISS) P25627 (/ISS)
RRNA (guanine) methyltransferase activity GO:0016435
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylguanine.
3 Q58DP0 (/ISS) Q9CY21 (/ISS) Q9CY21 (/ISS)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
3 Q58DP0 (/ISS) Q9CY21 (/ISS) Q9CY21 (/ISS)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
2 O43709 (/HDA) O43709 (/HDA)
Methyltransferase activity GO:0008168
Catalysis of the transfer of a methyl group to an acceptor molecule.
2 O43709 (/NAS) O43709 (/NAS)
RRNA (guanine) methyltransferase activity GO:0016435
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylguanine.
2 Q9CY21 (/ISO) Q9CY21 (/ISO)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
2 O43709 (/IDA) O43709 (/IDA)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
2 Q9CY21 (/ISO) Q9CY21 (/ISO)

There are 15 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RRNA (guanine-N7)-methylation GO:0070476
The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an rRNA molecule.
9 O43709 (/IMP) O43709 (/IMP) P25627 (/IMP) P25627 (/IMP) P25627 (/IMP) P25627 (/IMP) P25627 (/IMP) P25627 (/IMP) P25627 (/IMP)
Ribosomal small subunit export from nucleus GO:0000056
The directed movement of a ribosomal small subunit from the nucleus into the cytoplasm.
7 P25627 (/IMP) P25627 (/IMP) P25627 (/IMP) P25627 (/IMP) P25627 (/IMP) P25627 (/IMP) P25627 (/IMP)
Cellular bud site selection GO:0000282
The specification of the site where a daughter cell will form, in organisms that reproduce by budding. An example of this process is found in Saccharomyces cerevisiae.
7 P25627 (/HMP) P25627 (/HMP) P25627 (/HMP) P25627 (/HMP) P25627 (/HMP) P25627 (/HMP) P25627 (/HMP)
Endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0000447
Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
7 P25627 (/IMP) P25627 (/IMP) P25627 (/IMP) P25627 (/IMP) P25627 (/IMP) P25627 (/IMP) P25627 (/IMP)
RRNA (guanine-N7)-methylation GO:0070476
The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an rRNA molecule.
3 Q58DP0 (/ISS) Q9CY21 (/ISS) Q9CY21 (/ISS)
Positive regulation of rRNA processing GO:2000234
Any process that activates or increases the frequency, rate or extent of rRNA processing.
3 Q58DP0 (/ISS) Q9CY21 (/ISS) Q9CY21 (/ISS)
RRNA processing GO:0006364
Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
2 Q9LVD0 (/IMP) Q9LVD0 (/IMP)
Maintenance of root meristem identity GO:0010078
The process in which an organism retains a population of root meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.
2 Q9LVD0 (/IMP) Q9LVD0 (/IMP)
RRNA methylation GO:0031167
The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule.
2 O43709 (/TAS) O43709 (/TAS)
Root development GO:0048364
The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo.
2 Q9LVD0 (/IMP) Q9LVD0 (/IMP)
Lateral root development GO:0048527
The process whose specific outcome is the progression of the lateral root over time, from its formation to the mature structure. A lateral root is one formed from pericycle cells located on the xylem radius of the root, as opposed to the initiation of the main root from the embryo proper.
2 Q9LVD0 (/IMP) Q9LVD0 (/IMP)
RRNA (guanine-N7)-methylation GO:0070476
The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an rRNA molecule.
2 Q9CY21 (/ISO) Q9CY21 (/ISO)
Callus formation GO:1990110
The process by which a callus is formed at a wound site. A plant callus is a portion of plant tissue that consists of mass of undifferentiated plant cells. It consists primarily of parenchyma cells but possibly contains other cell types as the callus begins to differentiate.
2 Q9LVD0 (/IMP) Q9LVD0 (/IMP)
Positive regulation of rRNA processing GO:2000234
Any process that activates or increases the frequency, rate or extent of rRNA processing.
2 O43709 (/IMP) O43709 (/IMP)
Positive regulation of rRNA processing GO:2000234
Any process that activates or increases the frequency, rate or extent of rRNA processing.
2 Q9CY21 (/ISO) Q9CY21 (/ISO)

There are 13 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
11 O43709 (/IDA) O43709 (/IDA) P25627 (/IDA) P25627 (/IDA) P25627 (/IDA) P25627 (/IDA) P25627 (/IDA) P25627 (/IDA) P25627 (/IDA) Q9LVD0 (/IDA)
(1 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
7 P25627 (/HDA) P25627 (/HDA) P25627 (/HDA) P25627 (/HDA) P25627 (/HDA) P25627 (/HDA) P25627 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
7 P25627 (/HDA) P25627 (/HDA) P25627 (/HDA) P25627 (/HDA) P25627 (/HDA) P25627 (/HDA) P25627 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 O43709 (/IDA) O43709 (/IDA) Q9LVD0 (/IDA) Q9LVD0 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
3 Q58DP0 (/ISS) Q9CY21 (/ISS) Q9CY21 (/ISS)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
3 Q58DP0 (/ISS) Q9CY21 (/ISS) Q9CY21 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q9CY21 (/ISO) Q9CY21 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 O43709 (/IDA) O43709 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 Q9CY21 (/ISO) Q9CY21 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 O43709 (/TAS) O43709 (/TAS)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
2 Q9CY21 (/ISO) Q9CY21 (/ISO)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
2 O43709 (/IDA) O43709 (/IDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
2 Q9CY21 (/ISO) Q9CY21 (/ISO)
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