The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 124: HEN methyltransferase 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
O-methyltransferase activity GO:0008171
Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.
8 C0IN03 (/ISS) E1BVR9 (/ISS) Q32PY6 (/ISS) Q4R3W5 (/ISS) Q4R3W5 (/ISS) Q4R3W5 (/ISS) Q5T8I9 (/ISS) Q5T8I9 (/ISS)
RNA methyltransferase activity GO:0008173
Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an RNA molecule.
8 C0IN03 (/ISS) E1BVR9 (/ISS) Q32PY6 (/ISS) Q4R3W5 (/ISS) Q4R3W5 (/ISS) Q4R3W5 (/ISS) Q5T8I9 (/ISS) Q5T8I9 (/ISS)
O-methyltransferase activity GO:0008171
Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.
3 Q568P9 (/IDA) Q7K175 (/IDA) Q8CAE2 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q5T8I9 (/IPI) Q5T8I9 (/IPI)
RNA methyltransferase activity GO:0008173
Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an RNA molecule.
2 Q568P9 (/IDA) Q8CAE2 (/IDA)
O-methyltransferase activity GO:0008171
Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.
1 Q8CAE2 (/EXP)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA methylation GO:0001510
Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonucleotide. Usually uses S-adenosylmethionine as a cofactor.
8 C0IN03 (/ISS) E1BVR9 (/ISS) Q32PY6 (/ISS) Q4R3W5 (/ISS) Q4R3W5 (/ISS) Q4R3W5 (/ISS) Q5T8I9 (/ISS) Q5T8I9 (/ISS)
PiRNA metabolic process GO:0034587
The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
8 C0IN03 (/ISS) E1BVR9 (/ISS) Q32PY6 (/ISS) Q4R3W5 (/ISS) Q4R3W5 (/ISS) Q4R3W5 (/ISS) Q5T8I9 (/ISS) Q5T8I9 (/ISS)
RNA methylation GO:0001510
Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonucleotide. Usually uses S-adenosylmethionine as a cofactor.
3 Q568P9 (/IDA) Q7K175 (/IDA) Q8CAE2 (/IDA)
PiRNA metabolic process GO:0034587
The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
2 Q7K175 (/IDA) Q8CAE2 (/IDA)
RNA methylation GO:0001510
Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonucleotide. Usually uses S-adenosylmethionine as a cofactor.
1 Q7K175 (/IMP)
Production of siRNA involved in RNA interference GO:0030422
Cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of RNA interference.
1 Q7K175 (/IDA)
PiRNA metabolic process GO:0034587
The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
1 Q568P9 (/IMP)
Posttranscriptional gene silencing by RNA GO:0035194
Any process of posttranscriptional gene inactivation (silencing) mediated by small RNA molecules that may trigger RNA (often mRNA) degradation or negatively regulate mRNA translation.
1 Q7K175 (/IMP)
Oocyte development GO:0048599
The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
1 Q568P9 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
P granule GO:0043186
A small cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.
9 C0IN03 (/ISS) E1BVR9 (/ISS) Q32PY6 (/ISS) Q4R3W5 (/ISS) Q4R3W5 (/ISS) Q4R3W5 (/ISS) Q5T8I9 (/ISS) Q5T8I9 (/ISS) Q8CAE2 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q8CAE2 (/TAS)
P granule GO:0043186
A small cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.
1 Q568P9 (/IDA)
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