A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.

The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.

A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.

Processing which a protein carries out itself. This involves actions such as the autolytic removal of residues to generate the mature form of the protein.

The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.

Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process.

A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.

Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development.

Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to manganese ion.

Any process that activates or increases the frequency, rate or extent of cellular response to gamma radiation.

The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.

Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process.

Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process.

Any process that increases the rate, frequency or extent of protein maturation by peptide bond cleavage.

Processing which a protein carries out itself. This involves actions such as the autolytic removal of residues to generate the mature form of the protein.

Disassembly of actin filaments by the removal of actin monomers from a filament.

Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.

Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.

Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.

Any process that modulates the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.

Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached.

Any process that mediates the adoption of a specific fate by a cell.

The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state.

Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).

Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.

Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase.

Any process that activates or increases the frequency, rate or extent of oviposition.

Any process that activates or increases the frequency, rate or extent of oviposition.

Any apoptotic process that is involved in anatomical structure development.

Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development.

Any process that activates or increases the frequency, rate or extent of synapse pruning.

Any process that activates or increases the frequency, rate or extent of synapse pruning.

Any process that activates or increases the frequency, rate or extent of cellular response to gamma radiation.

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

Cytoplasm situated near, or occurring around, the nucleus.

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

A protein complex that is located in the cytosol and contains one or more cysteine-type endopeptidases (also called caspases), which give the complex a peptidase activity with specificity for the hydrolysis of aspartyl bonds. These complexes may be involved e.g. in apoptotic or inflammation processes.

The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.

The nucleus of a germ cell, a reproductive cell in multicellular organisms.

Cytoplasm situated near, or occurring around, the nucleus.

The part of a synapse that is part of the presynaptic cell.