The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Caspase-3 preproprotein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 37 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
11 G3IL63 (/IPI) O01382 (/IPI) O02002 (/IPI) O08738 (/IPI) O08738 (/IPI) P42574 (/IPI) P42574 (/IPI) P55212 (/IPI) P55213 (/IPI) P70677 (/IPI)
(1 more)
Cysteine-type endopeptidase activity involved in apoptotic signaling pathway GO:0097199
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic signaling pathway.
11 P55213 (/ISS) P70677 (/ISS) Q5IS54 (/ISS) Q5IS54 (/ISS) Q5IS99 (/ISS) Q60431 (/ISS) Q60431 (/ISS) Q8MJU1 (/ISS) Q8MKI5 (/ISS) Q8MKI5 (/ISS)
(1 more)
Peptidase activity GO:0008233
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
6 A0A1C9CJ76 (/IDA) B8JK21 (/IDA) P42574 (/IDA) P42574 (/IDA) P70677 (/IDA) Q98UI8 (/IDA)
Cysteine-type endopeptidase activity GO:0004197
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
5 O01382 (/IDA) O02002 (/IDA) P42574 (/IDA) P42574 (/IDA) P70677 (/IDA)
Cysteine-type endopeptidase activity GO:0004197
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
4 O01382 (/TAS) O02002 (/TAS) P42574 (/TAS) P42574 (/TAS)
Peptidase activity GO:0008233
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
4 A0A1C9CJ76 (/IMP) B8JK21 (/IMP) P70677 (/IMP) Q98UI8 (/IMP)
Cysteine-type endopeptidase activity involved in apoptotic process GO:0097153
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic process.
4 O01382 (/IDA) P42574 (/IDA) P42574 (/IDA) P70677 (/IDA)
Cysteine-type endopeptidase activity involved in execution phase of apoptosis GO:0097200
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the execution phase of apoptosis.
4 O02002 (/IMP) P42574 (/IMP) P42574 (/IMP) P55212 (/IMP)
Endopeptidase activity GO:0004175
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.
3 O08738 (/IDA) O08738 (/IDA) O35397 (/IDA)
Peptidase activity GO:0008233
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
3 O08738 (/RCA) O08738 (/RCA) P70677 (/RCA)
Cysteine-type peptidase activity GO:0008234
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
3 O93415 (/IDA) P55213 (/IDA) P70677 (/IDA)
Cysteine-type endopeptidase activity involved in execution phase of apoptosis GO:0097200
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the execution phase of apoptosis.
3 O08738 (/ISO) O08738 (/ISO) P70677 (/ISO)
Endopeptidase activity GO:0004175
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.
2 O08738 (/ISO) O08738 (/ISO)
Cysteine-type endopeptidase activity GO:0004197
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
2 O01382 (/ISS) O02002 (/ISS)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
2 O08738 (/ISO) O08738 (/ISO)
Cysteine-type endopeptidase activity involved in apoptotic process GO:0097153
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic process.
2 P42574 (/IMP) P42574 (/IMP)
Cysteine-type endopeptidase activity involved in apoptotic signaling pathway GO:0097199
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic signaling pathway.
2 P42574 (/IMP) P42574 (/IMP)
Cysteine-type endopeptidase activity involved in execution phase of apoptosis GO:0097200
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the execution phase of apoptosis.
2 O01382 (/IDA) P70677 (/IDA)
BIR domain binding GO:1990525
Interacting selectively and non-covalently with a Baculovirus Inhibitor of apoptosis protein Repeat (BIR) domain.
2 O01382 (/IPI) O02002 (/IPI)
Protease binding GO:0002020
Interacting selectively and non-covalently with any protease or peptidase.
1 P55213 (/IPI)
Protease binding GO:0002020
Interacting selectively and non-covalently with any protease or peptidase.
1 P70677 (/ISO)
Aspartic-type endopeptidase activity GO:0004190
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.
1 P70677 (/IDA)
Cysteine-type endopeptidase activity GO:0004197
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
1 O93415 (/IMP)
Cysteine-type endopeptidase activity GO:0004197
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
1 P70677 (/ISO)
Cyclin-dependent protein serine/threonine kinase inhibitor activity GO:0004861
Stops, prevents or reduces the activity of a cyclin-dependent protein serine/threonine kinase.
1 P70677 (/IMP)
Death receptor binding GO:0005123
Interacting selectively and non-covalently with any member of the death receptor (DR) family. The DR family falls within the tumor necrosis factor receptor superfamily and is characterized by a cytoplasmic region of ~80 residues termed the death domain (DD).
1 P55213 (/IPI)
Death receptor binding GO:0005123
Interacting selectively and non-covalently with any member of the death receptor (DR) family. The DR family falls within the tumor necrosis factor receptor superfamily and is characterized by a cytoplasmic region of ~80 residues termed the death domain (DD).
1 P70677 (/ISO)
Peptidase activity GO:0008233
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
1 P70677 (/ISO)
Cysteine-type peptidase activity GO:0008234
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
1 P70677 (/ISO)
Cysteine-type peptidase activity GO:0008234
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
1 P55212 (/TAS)
Phospholipase A2 activator activity GO:0016005
Increases the activity of the enzyme phospholipase A2.
1 P55213 (/IMP)
Phospholipase A2 activator activity GO:0016005
Increases the activity of the enzyme phospholipase A2.
1 P70677 (/ISO)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 P55212 (/IPI)
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
1 P55213 (/IPI)
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
1 P70677 (/ISO)
Cysteine-type endopeptidase activity involved in apoptotic process GO:0097153
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic process.
1 P70677 (/ISO)
Cysteine-type endopeptidase activity involved in apoptotic signaling pathway GO:0097199
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic signaling pathway.
1 P70677 (/ISO)

There are 146 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
10 P70677 (/ISS) Q5IS54 (/ISS) Q5IS54 (/ISS) Q5IS99 (/ISS) Q60431 (/ISS) Q60431 (/ISS) Q8MJU1 (/ISS) Q8MKI5 (/ISS) Q8MKI5 (/ISS) Q95ND5 (/ISS)
Positive regulation of amyloid-beta formation GO:1902004
Any process that activates or increases the frequency, rate or extent of amyloid-beta formation.
10 P70677 (/ISS) Q5IS54 (/ISS) Q5IS54 (/ISS) Q5IS99 (/ISS) Q60431 (/ISS) Q60431 (/ISS) Q8MJU1 (/ISS) Q8MKI5 (/ISS) Q8MKI5 (/ISS) Q95ND5 (/ISS)
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
9 Q5IS54 (/ISS) Q5IS54 (/ISS) Q5IS99 (/ISS) Q60431 (/ISS) Q60431 (/ISS) Q8MJU1 (/ISS) Q8MKI5 (/ISS) Q8MKI5 (/ISS) Q95ND5 (/ISS)
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
8 A0A1C9CJ76 (/IMP) B8JK21 (/IMP) O93415 (/IMP) P42574 (/IMP) P42574 (/IMP) P55213 (/IMP) P70677 (/IMP) Q98UI8 (/IMP)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
6 A0A1C9CJ76 (/IDA) B8JK21 (/IDA) P70677 (/IDA) Q8MKI5 (/IDA) Q8MKI5 (/IDA) Q98UI8 (/IDA)
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
5 O01382 (/IDA) P42574 (/IDA) P42574 (/IDA) P55212 (/IDA) P55213 (/IDA)
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
5 O01382 (/TAS) O35397 (/TAS) P42574 (/TAS) P42574 (/TAS) P55212 (/TAS)
Execution phase of apoptosis GO:0097194
A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
4 O02002 (/IMP) P42574 (/IMP) P42574 (/IMP) P70677 (/IMP)
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
3 O08738 (/ISO) O08738 (/ISO) P70677 (/ISO)
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
3 O08738 (/RCA) O08738 (/RCA) P70677 (/RCA)
Axonal fasciculation GO:0007413
The collection of axons into a bundle of rods, known as a fascicle.
3 O08738 (/ISO) O08738 (/ISO) P70677 (/ISO)
Intrinsic apoptotic signaling pathway in response to osmotic stress GO:0008627
A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to changes in intracellular ion homeostasis, and ends when the execution phase of apoptosis is triggered.
3 P70677 (/IDA) Q8MKI5 (/IDA) Q8MKI5 (/IDA)
Response to glucose GO:0009749
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
3 O08738 (/ISO) O08738 (/ISO) P70677 (/ISO)
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
3 P42574 (/IDA) P42574 (/IDA) P55213 (/IDA)
Response to hydrogen peroxide GO:0042542
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
3 O08738 (/ISO) O08738 (/ISO) P70677 (/ISO)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
3 O08738 (/ISO) O08738 (/ISO) P70677 (/ISO)
Positive regulation of neuron apoptotic process GO:0043525
Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process.
3 O08738 (/ISO) O08738 (/ISO) P70677 (/ISO)
Regulation of collateral sprouting in absence of injury GO:0048696
Any process that modulates the frequency, rate or extent of collateral sprouting in the absence of injury.
3 A0A1C9CJ76 (/IGI) B8JK21 (/IGI) Q98UI8 (/IGI)
Regulation of collateral sprouting in absence of injury GO:0048696
Any process that modulates the frequency, rate or extent of collateral sprouting in the absence of injury.
3 A0A1C9CJ76 (/IMP) B8JK21 (/IMP) Q98UI8 (/IMP)
Cellular response to antibiotic GO:0071236
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
3 A0A1C9CJ76 (/IDA) B8JK21 (/IDA) Q98UI8 (/IDA)
Cellular response to retinoic acid GO:0071300
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.
3 A0A1C9CJ76 (/IDA) B8JK21 (/IDA) Q98UI8 (/IDA)
Cellular response to xenobiotic stimulus GO:0071466
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms.
3 A0A1C9CJ76 (/IDA) B8JK21 (/IDA) Q98UI8 (/IDA)
Cellular response to staurosporine GO:0072734
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a staurosporine stimulus.
3 P42574 (/IMP) P42574 (/IMP) P55212 (/IMP)
Cellular response to staurosporine GO:0072734
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a staurosporine stimulus.
3 O08738 (/ISO) O08738 (/ISO) P70677 (/ISO)
Execution phase of apoptosis GO:0097194
A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
3 P42574 (/IDA) P42574 (/IDA) P70677 (/IDA)
Execution phase of apoptosis GO:0097194
A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
3 P42574 (/TAS) P42574 (/TAS) P55212 (/TAS)
Positive regulation of amyloid-beta formation GO:1902004
Any process that activates or increases the frequency, rate or extent of amyloid-beta formation.
3 P42574 (/IDA) P42574 (/IDA) P55213 (/IDA)
Acute inflammatory response to non-antigenic stimulus GO:0002525
An acute inflammatory response to non-antigenic stimuli such as heat or physical trauma.
2 O08738 (/ISO) O08738 (/ISO)
Apoptotic DNA fragmentation GO:0006309
The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments.
2 P42574 (/TAS) P42574 (/TAS)
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
2 O02002 (/IDA) P70677 (/IDA)
Axonal fasciculation GO:0007413
The collection of axons into a bundle of rods, known as a fascicle.
2 O35397 (/IMP) P55213 (/IMP)
Response to organic substance GO:0010033
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
2 O35397 (/IEP) P55213 (/IEP)
Response to metal ion GO:0010038
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.
2 O35397 (/IEP) P55213 (/IEP)
Response to iron ion GO:0010039
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
2 O08738 (/ISO) O08738 (/ISO)
Programmed cell death involved in cell development GO:0010623
The activation of endogenous cellular processes that result in the death of a cell as part of its development.
2 O01382 (/IMP) O02002 (/IMP)
Programmed cell death GO:0012501
A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.
2 O01382 (/IDA) O02002 (/IDA)
Regulation of macroautophagy GO:0016241
Any process that modulates the frequency, rate or extent of macroautophagy.
2 P42574 (/TAS) P42574 (/TAS)
Neuron remodeling GO:0016322
The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development.
2 O01382 (/IMP) O02002 (/IMP)
Cytokine-mediated signaling pathway GO:0019221
A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
2 P42574 (/TAS) P42574 (/TAS)
Erythrocyte differentiation GO:0030218
The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.
2 P42574 (/IDA) P42574 (/IDA)
Erythrocyte differentiation GO:0030218
The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.
2 P42574 (/TAS) P42574 (/TAS)
Platelet formation GO:0030220
The process in which platelets bud from long processes extended by megakaryocytes.
2 P42574 (/TAS) P42574 (/TAS)
Response to estradiol GO:0032355
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
2 O35397 (/IEP) P55213 (/IEP)
Response to cytokine GO:0034097
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
2 O08738 (/ISO) O08738 (/ISO)
Response to tumor necrosis factor GO:0034612
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.
2 P42574 (/TAS) P42574 (/TAS)
Hippo signaling GO:0035329
The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1.
2 P42574 (/TAS) P42574 (/TAS)
Response to hydrogen peroxide GO:0042542
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
2 O35397 (/IDA) P55213 (/IDA)
Regulation of apoptotic process GO:0042981
Any process that modulates the occurrence or rate of cell death by apoptotic process.
2 O08738 (/RCA) O08738 (/RCA)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
2 O35397 (/IMP) P55213 (/IMP)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
2 P42574 (/IGI) P42574 (/IGI)
Positive regulation of neuron apoptotic process GO:0043525
Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process.
2 O35397 (/IMP) P55213 (/IMP)
Nurse cell apoptotic process GO:0045476
Any apoptotic process in a nurse cell. During late oogenesis, following the transfer of substances from the nurse cells to the oocyte, nurse cell remnants are cleared from the egg chamber by apoptotic process.
2 O01382 (/IGI) O02002 (/IGI)
Positive regulation of retinal cell programmed cell death GO:0046670
Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the retina.
2 O08738 (/ISO) O08738 (/ISO)
Neurotrophin TRK receptor signaling pathway GO:0048011
A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription.
2 P42574 (/IDA) P42574 (/IDA)
Apoptotic signaling pathway GO:0097190
A series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.
2 P42574 (/TAS) P42574 (/TAS)
Extrinsic apoptotic signaling pathway in absence of ligand GO:0097192
A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with withdrawal of a ligand from a cell surface receptor, and ends when the execution phase of apoptosis is triggered.
2 P42574 (/TAS) P42574 (/TAS)
Luteolysis GO:0001554
The lysis or structural demise of the corpus luteum. During normal luteolysis, two closely related events occur. First, there is loss of the capacity to synthesize and secrete progesterone (functional luteolysis) followed by loss of the cells that comprise the corpus luteum (structural luteolysis). Preventing luteolysis is crucial to maintain pregnancy.
1 P55213 (/IEP)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
1 P55213 (/IEP)
B cell homeostasis GO:0001782
The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
1 P70677 (/IMP)
Lens development in camera-type eye GO:0002088
The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.
1 O35397 (/IEP)
Acute inflammatory response to non-antigenic stimulus GO:0002525
An acute inflammatory response to non-antigenic stimuli such as heat or physical trauma.
1 O35397 (/IDA)
Apoptotic DNA fragmentation GO:0006309
The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments.
1 O93415 (/IGI)
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
1 O93415 (/IGI)
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
1 P55212 (/TAS)
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
1 P70677 (/ISO)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
1 P70677 (/IDA)
Multicellular organism development GO:0007275
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
1 O02002 (/TAS)
Ovarian nurse cell to oocyte transport GO:0007300
Transfer of constituents synthesized in the ovarian nurse cells to the oocyte, through the ring canals, as the egg chamber is growing. An example of this is found in Drosophila melanogaster.
1 O02002 (/TAS)
Cytoplasmic transport, nurse cell to oocyte GO:0007303
The directed movement of cytoplasmic constituents synthesized in the nurse cells to the oocyte.
1 O02002 (/TAS)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
1 P70677 (/IGI)
Sensory perception of sound GO:0007605
The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.
1 P70677 (/IMP)
Learning or memory GO:0007611
The acquisition and processing of information and/or the storage and retrieval of this information over time.
1 P55213 (/IMP)
Learning or memory GO:0007611
The acquisition and processing of information and/or the storage and retrieval of this information over time.
1 P70677 (/ISO)
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
1 O02002 (/IMP)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
1 O35397 (/IEP)
Response to UV GO:0009411
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
1 P70677 (/IDA)
Response to UV GO:0009411
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
1 P70677 (/IGI)
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
1 P70677 (/IDA)
Response to glucose GO:0009749
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
1 P55213 (/IDA)
Response to glucose GO:0009749
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
1 O35397 (/IMP)
Response to organic substance GO:0010033
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
1 P70677 (/IDA)
Response to iron ion GO:0010039
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
1 O35397 (/IMP)
Response to X-ray GO:0010165
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).
1 P55213 (/IEP)
Response to X-ray GO:0010165
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).
1 O01382 (/IMP)
Response to organonitrogen compound GO:0010243
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.
1 O35397 (/IEP)
Response to gamma radiation GO:0010332
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.
1 O35397 (/IEP)
Positive regulation of autophagy GO:0010508
Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
1 O02002 (/IDA)
Programmed cell death GO:0012501
A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.
1 O01382 (/IMP)
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
1 P55213 (/IEP)
Positive regulation of macroautophagy GO:0016239
Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation.
1 O02002 (/IMP)
Protein processing GO:0016485
Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
1 P70677 (/IDA)
Hippocampus development GO:0021766
The progression of the hippocampus over time from its initial formation until its mature state.
1 P55213 (/IEP)
Neuron differentiation GO:0030182
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
1 P55213 (/IEP)
Keratinocyte differentiation GO:0030216
The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte.
1 P70677 (/IMP)
Erythrocyte differentiation GO:0030218
The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.
1 P70677 (/ISO)
Apoptotic nuclear changes GO:0030262
Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis.
1 O93415 (/IGI)
Apoptotic chromosome condensation GO:0030263
The compaction of chromatin during apoptosis.
1 O93415 (/IGI)
Epithelial cell differentiation GO:0030855
The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium.
1 P55212 (/IEP)
Negative regulation of B cell proliferation GO:0030889
Any process that stops, prevents or reduces the rate or extent of B cell proliferation.
1 P70677 (/IMP)
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
1 P70677 (/ISO)
Response to cobalt ion GO:0032025
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus.
1 P55213 (/IEP)
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
1 P55213 (/IEP)
Response to testosterone GO:0033574
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.
1 O35397 (/IEP)
Response to cytokine GO:0034097
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
1 O35397 (/IDA)
Glial cell apoptotic process GO:0034349
Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system.
1 P55213 (/IEP)
Glial cell apoptotic process GO:0034349
Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system.
1 P70677 (/IMP)
Salivary gland histolysis GO:0035070
The stage-specific break down of the larval salivary glands during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly.
1 O01382 (/IMP)
Response to nicotine GO:0035094
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.
1 P55213 (/IEP)
Sterol regulatory element binding protein cleavage GO:0035103
The proteolytic release of a transcriptionally active sterol regulatory element binding protein (SREBP) from intracellular membranes, freeing it to move to the nucleus to upregulate transcription of target genes, in response to altered levels of one or more lipids.
1 O01382 (/IDA)
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
1 P55213 (/IMP)
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
1 P70677 (/ISO)
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
1 P55213 (/IEP)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 P55213 (/IEP)
Regulation of apoptotic process GO:0042981
Any process that modulates the occurrence or rate of cell death by apoptotic process.
1 P55212 (/TAS)
T cell homeostasis GO:0043029
The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
1 P70677 (/IMP)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 P70677 (/ISO)
Response to amino acid GO:0043200
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
1 P55213 (/IEP)
Cell fate commitment GO:0045165
The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.
1 P70677 (/IMP)
Nurse cell apoptotic process GO:0045476
Any apoptotic process in a nurse cell. During late oogenesis, following the transfer of substances from the nurse cells to the oocyte, nurse cell remnants are cleared from the egg chamber by apoptotic process.
1 O02002 (/IMP)
Nurse cell apoptotic process GO:0045476
Any apoptotic process in a nurse cell. During late oogenesis, following the transfer of substances from the nurse cells to the oocyte, nurse cell remnants are cleared from the egg chamber by apoptotic process.
1 O02002 (/TAS)
Negative regulation of cyclin-dependent protein serine/threonine kinase activity GO:0045736
Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.
1 P70677 (/IMP)
Negative regulation of cell cycle GO:0045786
Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.
1 P70677 (/IMP)
Negative regulation of activated T cell proliferation GO:0046007
Any process that stops, prevents or reduces the rate or extent of activated T cell proliferation.
1 P70677 (/IMP)
Regulation of retinal cell programmed cell death GO:0046668
Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the retina.
1 O01382 (/NAS)
Positive regulation of retinal cell programmed cell death GO:0046670
Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the retina.
1 O35397 (/IMP)
Positive regulation of compound eye retinal cell programmed cell death GO:0046672
Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the compound eye retina.
1 O01382 (/IMP)
Response to antibiotic GO:0046677
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
1 P55213 (/IEP)
Neurotrophin TRK receptor signaling pathway GO:0048011
A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription.
1 P70677 (/ISO)
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
1 O02002 (/IMP)
Spermatid differentiation GO:0048515
The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
1 O01382 (/IMP)
Striated muscle cell differentiation GO:0051146
The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle.
1 P55213 (/IEP)
Response to glucocorticoid GO:0051384
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
1 P55213 (/IEP)
Neuron apoptotic process GO:0051402
Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.
1 P70677 (/IDA)
Neuron apoptotic process GO:0051402
Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.
1 P70677 (/IGI)
Neuron apoptotic process GO:0051402
Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.
1 P70677 (/IMP)
Anterior neural tube closure GO:0061713
The step in the formation of the neural tube, where the paired anterior neural folds are brought together and fuse at the dorsal midline.
1 P70677 (/IMP)
Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059
A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
1 P70677 (/NAS)
Lens fiber cell differentiation GO:0070306
The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities.
1 O93415 (/TAS)
Cellular response to organic substance GO:0071310
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
1 P70677 (/IDA)
Cellular response to organic cyclic compound GO:0071407
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
1 P55213 (/IEP)
Leukocyte apoptotic process GO:0071887
Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.
1 P55213 (/IEP)
Execution phase of apoptosis GO:0097194
A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
1 P70677 (/IGI)
Execution phase of apoptosis GO:0097194
A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
1 P70677 (/ISO)
Negative regulation of neuromuscular synaptic transmission GO:1900074
Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular synaptic transmission.
1 O02002 (/IMP)
Positive regulation of amyloid-beta formation GO:1902004
Any process that activates or increases the frequency, rate or extent of amyloid-beta formation.
1 P70677 (/ISO)
Positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway GO:2001269
Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway.
1 O01382 (/IDA)

There are 24 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
7 O01382 (/IDA) O35397 (/IDA) P55213 (/IDA) P70677 (/IDA) Q8MKI5 (/IDA) Q8MKI5 (/IDA) Q95ND5 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 O35397 (/IDA) P42574 (/IDA) P42574 (/IDA) P70677 (/IDA) Q95ND5 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5 O35397 (/IDA) P42574 (/IDA) P42574 (/IDA) P55212 (/IDA) P55213 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 P42574 (/TAS) P42574 (/TAS) P55212 (/TAS) P70677 (/TAS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 O08738 (/ISO) O08738 (/ISO) P70677 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
3 P42574 (/TAS) P42574 (/TAS) P55212 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 O08738 (/ISO) O08738 (/ISO) P70677 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 O08738 (/ISO) O08738 (/ISO) P70677 (/ISO)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
3 O02002 (/IDA) O35397 (/IDA) P55213 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
3 O08738 (/ISO) O08738 (/ISO) P70677 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 O08738 (/ISO) O08738 (/ISO)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
2 O08738 (/ISO) O08738 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 P55212 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 O02002 (/IDA)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
1 G3IL63 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O02002 (/ISS)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
1 O35397 (/IDA)
Death-inducing signaling complex GO:0031264
A protein complex formed by the association of signaling proteins with a death receptor upon ligand binding. The complex includes procaspases and death domain-containing proteins in addition to the ligand-bound receptor, and may control the activation of caspases 8 and 10.
1 P55213 (/IDA)
Death-inducing signaling complex GO:0031264
A protein complex formed by the association of signaling proteins with a death receptor upon ligand binding. The complex includes procaspases and death domain-containing proteins in addition to the ligand-bound receptor, and may control the activation of caspases 8 and 10.
1 P70677 (/ISO)
Mitochondrial membrane GO:0031966
Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.
1 G3IL63 (/TAS)
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
1 P55213 (/IDA)
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
1 P70677 (/ISO)
Neuronal ribonucleoprotein granule GO:0071598
A ribonucleoprotein complex that is found in the cytoplasm of axons and dendrites, and transports translationally silenced mRNAs to dendritic synapses, where they are released and translated in response to specific exogenous stimuli.
1 O02002 (/IDA)
Messenger ribonucleoprotein complex GO:1990124
A ribonucleoprotein complex containing both protein and messenger RNA (mRNA) molecules.
1 O02002 (/IDA)