The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Tubulin/FtsZ, GTPase domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Tubulin beta chain

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
16 P24636 (/IPI) P24636 (/IPI) P29513 (/IPI) P29513 (/IPI) P29516 (/IPI) P29516 (/IPI) P29517 (/IPI) P29517 (/IPI) Q56YW9 (/IPI) Q56YW9 (/IPI)
(6 more)
Structural constituent of cytoskeleton GO:0005200
The action of a molecule that contributes to the structural integrity of a cytoskeletal structure.
11 P24636 (/ISS) P24636 (/ISS) P29513 (/ISS) P29513 (/ISS) P29514 (/ISS) P29514 (/ISS) P29514 (/ISS) P29515 (/ISS) P29515 (/ISS) P29516 (/ISS)
(1 more)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
2 P29517 (/IDA) P29517 (/IDA)

There are 19 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell growth GO:0016049
The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.
15 B1PBV8 (/IMP) B1PBV8 (/IMP) B1PBV9 (/IMP) B1PBW1 (/IMP) B1PBW4 (/IMP) B1PBW6 (/IMP) B1PBW7 (/IMP) B1PBW7 (/IMP) Q4TZT6 (/IMP) Q6VAF5 (/IMP)
(5 more)
Seed trichome elongation GO:0090378
The process in which a seed trichome irreversibly increases in size in one
10 B1PBV9 (/IMP) B1PBW1 (/IMP) Q4TZT6 (/IMP) Q6VAF5 (/IMP) Q6VAF5 (/IMP) Q6VAF7 (/IMP) Q6VAF8 (/IMP) Q8H6N0 (/IMP) Q8RU83 (/IMP) Q8RU83 (/IMP)
Microtubule-based process GO:0007017
Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins.
9 P29513 (/ISS) P29513 (/ISS) P29514 (/ISS) P29514 (/ISS) P29514 (/ISS) P29515 (/ISS) P29515 (/ISS) P29516 (/ISS) P29516 (/ISS)
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
7 P29514 (/IEP) P29514 (/IEP) P29514 (/IEP) P29515 (/IEP) P29515 (/IEP) P29516 (/IEP) P29516 (/IEP)
Response to brassinosteroid GO:0009741
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus.
6 B1PBW6 (/IEP) Q4TZT6 (/IEP) Q6VAF8 (/IEP) Q8H6N0 (/IEP) Q8RU83 (/IEP) Q8RU83 (/IEP)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
4 P29515 (/IEP) P29515 (/IEP) P29517 (/IEP) P29517 (/IEP)
Root development GO:0048364
The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo.
4 B1PBW2 (/IEP) B1PBW6 (/IEP) B1PBW7 (/IEP) B1PBW7 (/IEP)
Leaf development GO:0048366
The process whose specific outcome is the progression of the leaf over time, from its formation to the mature structure.
4 B1PBW2 (/IEP) B1PBW7 (/IEP) B1PBW7 (/IEP) Q8H6N0 (/IEP)
Response to fatty acid GO:0070542
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.
4 Q4TZT6 (/IEP) Q8H6N0 (/IEP) Q8RU83 (/IEP) Q8RU83 (/IEP)
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
3 P29514 (/IEP) P29514 (/IEP) P29514 (/IEP)
Response to gibberellin GO:0009739
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus.
3 Q8H6N0 (/IEP) Q8RU83 (/IEP) Q8RU83 (/IEP)
Response to light stimulus GO:0009416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
2 P12411 (/IEP) P12411 (/IEP)
Response to light stimulus GO:0009416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
2 Q8RU83 (/ISA) Q8RU83 (/ISA)
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
2 Q8RU83 (/ISA) Q8RU83 (/ISA)
Response to ethylene GO:0009723
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.
2 Q4TZT6 (/IEP) Q6VAF7 (/IEP)
Unidimensional cell growth GO:0009826
The process in which a cell irreversibly increases in size in one
2 P12411 (/IEP) P12411 (/IEP)
Unidimensional cell growth GO:0009826
The process in which a cell irreversibly increases in size in one
2 Q8RU83 (/ISA) Q8RU83 (/ISA)
Secondary cell wall biogenesis involved in seed trichome differentiation GO:0090379
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall of seed trichomes after cell expansion is complete.
2 B1PBV8 (/IEP) B1PBV8 (/IEP)
Seed trichome elongation GO:0090378
The process in which a seed trichome irreversibly increases in size in one
1 B1PBW0 (/IEP)

There are 16 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
11 P24636 (/IDA) P24636 (/IDA) P29513 (/IDA) P29513 (/IDA) P29514 (/IDA) P29514 (/IDA) P29514 (/IDA) P29515 (/IDA) P29515 (/IDA) P29517 (/IDA)
(1 more)
Tubulin complex GO:0045298
A heterodimer of tubulins alpha and beta that constitutes the protomer for microtubule assembly.
10 P24636 (/ISS) P24636 (/ISS) P29513 (/ISS) P29513 (/ISS) P29515 (/ISS) P29515 (/ISS) P29516 (/ISS) P29516 (/ISS) P29517 (/ISS) P29517 (/ISS)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
8 P24636 (/IDA) P24636 (/IDA) P29515 (/IDA) P29515 (/IDA) P29516 (/IDA) P29516 (/IDA) P29517 (/IDA) P29517 (/IDA)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
6 P24636 (/IDA) P24636 (/IDA) P29513 (/IDA) P29513 (/IDA) P29515 (/IDA) P29515 (/IDA)
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
6 P24636 (/IDA) P24636 (/IDA) P29515 (/IDA) P29515 (/IDA) P29517 (/IDA) P29517 (/IDA)
Vacuole GO:0005773
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
4 P12411 (/IDA) P12411 (/IDA) P29515 (/IDA) P29515 (/IDA)
Vacuolar membrane GO:0005774
The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.
4 P29513 (/IDA) P29513 (/IDA) P29517 (/IDA) P29517 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 P24636 (/IDA) P24636 (/IDA) P29515 (/IDA) P29515 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
4 P29513 (/IDA) P29513 (/IDA) P29517 (/IDA) P29517 (/IDA)
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
4 P24636 (/IDA) P24636 (/IDA) P29513 (/IDA) P29513 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
4 P29513 (/IDA) P29513 (/IDA) P29516 (/IDA) P29516 (/IDA)
Microtubule cytoskeleton GO:0015630
The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
3 P29514 (/ISS) P29514 (/ISS) P29514 (/ISS)
Vacuole GO:0005773
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
2 Q8RU83 (/ISA) Q8RU83 (/ISA)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
2 Q8RU83 (/ISA) Q8RU83 (/ISA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 Q8RU83 (/ISA) Q8RU83 (/ISA)
Apoplast GO:0048046
The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it.
2 P24636 (/IDA) P24636 (/IDA)
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