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CATH Superfamily 3.40.50.12780

ANL, N-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
N-terminal domain of ligase-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 15: D-alanine--D-alanyl carrier protein ligase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
D-alanine--[D-alanyl-carrier protein] ligase. [EC: 6.2.1.54]
ATP + D-alanine + holo-[D-alaninyl-carrier protein] = AMP + diphosphate + D-alanyl-[D-alanyl-carrier protein].
  • The enzyme is involved in the modification of wall teichoic acids, as well as type I and IV lipoteichoic acids, with D-alanine residues.
  • It activates D-alanine using ATP to form a high-energy (D-alanyl)adenylate intermediate and subsequently transfers the alanyl moiety to the phosphopantheinyl prosthetic group of a D-alanyl-carrier protein (DltC).
 1302 A0A0B5UW14 A0A0B5UW14 A0A0B5UW14 A0A0B5UW14 A0A0B5WGE9 A0A0B5WGE9 A0A0B5WGE9 A0A0B5WGE9 A0A0B5WGE9 A0A0B5WGE9
(1292 more...)