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CATH Superfamily 3.40.50.12440

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Anaerobic dimethyl sulfoxide reductase, A subunit

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Respiratory dimethylsulfoxide reductase. [EC: 1.8.5.3]
Dimethylsulfide + menaquinone + H(2)O = dimethylsulfoxide + menaquinol.
  • The enzyme participates in bacterial electron transfer pathways in which dimethylsulfoxide (DMSO) is the terminal electron acceptor.
  • It is composed of three subunits - DmsA contains a bis(guanylyl molybdopterin) cofactor and a [4Fe-4S] cluster, DmsB is an iron- sulfur protein, and DmsC is a transmembrane protein that anchors the enzyme and accepts electrons from the quinol pool.
  • The electrons are passed through DmsB to DmsA and on to DMSO.
  • The enzyme can also reduce pyridine-N-oxide and trimethylamine N-oxide to the corresponding amines with lower activity.
 812 A0A023YU66 A0A023YU66 A0A023YU66 A0A023YU66 A0A023YU66 A0A023YU66 A0A023YU66 A0A023YU66 A0A023YU66 A0A023YU66
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