The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphoglycerate mutase-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 21: Acid phosphatase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Acid phosphatase activity GO:0003993
Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an acid pH optimum.
10 P00635 (/IDA) P00635 (/IDA) P35842 (/IDA) P35842 (/IDA) P38693 (/IDA) P38693 (/IDA) P38693 (/IDA) P38693 (/IDA) P38693 (/IDA) Q5AMR2 (/IDA)
Acid phosphatase activity GO:0003993
Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an acid pH optimum.
5 P52290 (/ISS) P52290 (/ISS) P52290 (/ISS) P52290 (/ISS) P52290 (/ISS)
Nucleoside-triphosphatase activity GO:0017111
Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate.
2 P00635 (/IGI) P00635 (/IGI)
Nucleoside-triphosphatase activity GO:0017111
Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate.
2 P00635 (/IMP) P00635 (/IMP)
Nucleoside-triphosphate diphosphatase activity GO:0047429
Catalysis of the reaction: H2O + a nucleoside triphosphate = diphosphate + a nucleotide.
2 P00635 (/IGI) P00635 (/IGI)
Nucleoside-triphosphate diphosphatase activity GO:0047429
Catalysis of the reaction: H2O + a nucleoside triphosphate = diphosphate + a nucleotide.
2 P00635 (/IMP) P00635 (/IMP)
Acid phosphatase activity GO:0003993
Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an acid pH optimum.
1 P24031 (/IMP)
4-phytase activity GO:0008707
Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = 1-myo-inositol 1,2,3,4,5-pentakisphosphate + phosphate.
1 A0A1D8PS71 (/IMP)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Invasive growth in response to glucose limitation GO:0001403
A growth pattern exhibited by budding haploid cells under certain growth conditions, in which cells retain the typical axial budding pattern of haploids, but become elongated and fail to separate after division; during growth on a solid substrate, this results in penetration of cells into the agar medium. An example of this process is found in Saccharomyces cerevisiae.
5 P52290 (/IGI) P52290 (/IGI) P52290 (/IGI) P52290 (/IGI) P52290 (/IGI)
Pseudohyphal growth GO:0007124
A pattern of cell growth that occurs in conditions of nitrogen limitation and abundant fermentable carbon source. Cells become elongated, switch to a unipolar budding pattern, remain physically attached to each other, and invade the growth substrate.
5 P52290 (/IMP) P52290 (/IMP) P52290 (/IMP) P52290 (/IMP) P52290 (/IMP)
Phosphate-containing compound metabolic process GO:0006796
The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
2 P00635 (/IMP) P00635 (/IMP)
Phosphate-containing compound metabolic process GO:0006796
The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
2 P35842 (/TAS) P35842 (/TAS)
Regulation of cell size GO:0008361
Any process that modulates the size of a cell.
2 P00635 (/HMP) P00635 (/HMP)
Cellular response to phosphate starvation GO:0016036
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate.
2 P00635 (/IMP) P00635 (/IMP)
Phosphate-containing compound metabolic process GO:0006796
The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
1 P24031 (/IDA)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
1 A0A1D8PS71 (/IMP)
Hyphal growth GO:0030448
Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls.
1 A0A1D8PS71 (/IMP)
Myo-inositol hexakisphosphate dephosphorylation GO:0033518
The process of removing one or more phosphate group from myo-inositol hexakisphosphate.
1 A0A1D8PS71 (/IMP)
Thiamine-containing compound metabolic process GO:0042723
The chemical reactions and pathways involving thiamine (vitamin B1), and compounds derived from it.
1 P24031 (/IDA)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell periphery GO:0071944
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
9 P00635 (/HDA) P00635 (/HDA) P35842 (/HDA) P35842 (/HDA) P52290 (/HDA) P52290 (/HDA) P52290 (/HDA) P52290 (/HDA) P52290 (/HDA)
Fungal-type cell wall GO:0009277
A rigid yet dynamic structure surrounding the plasma membrane that affords protection from stresses and contributes to cell morphogenesis, consisting of extensively cross-linked glycoproteins and carbohydrates. The glycoproteins may be modified with N- or O-linked carbohydrates, or glycosylphosphatidylinositol (GPI) anchors; the polysaccharides are primarily branched glucans, including beta-linked and alpha-linked glucans, and may also include chitin and other carbohydrate polymers, but not cellulose or pectin. Enzymes involved in cell wall biosynthesis are also found in the cell wall. Note that some forms of fungi develop a capsule outside of the cell wall under certain circumstances; this is considered a separate structure.
7 P00635 (/IDA) P00635 (/IDA) P52290 (/IDA) P52290 (/IDA) P52290 (/IDA) P52290 (/IDA) P52290 (/IDA)
Fungal-type vacuole GO:0000324
A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure.
5 P38693 (/HDA) P38693 (/HDA) P38693 (/HDA) P38693 (/HDA) P38693 (/HDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
2 P35842 (/IDA) P35842 (/IDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
2 A0A1D8PS71 (/IDA) Q59UY6 (/IDA)
Cell wall-bounded periplasmic space GO:0030287
The region between the plasma membrane and the cell wall in organisms lacking an outer cell membrane such as yeast and Gram positive bacteria. The region is thinner than the equivalent in Gram negative bacteria.
2 A0A1D8PS71 (/IDA) Q59UY6 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 P24031 (/HDA)
Cell wall-bounded periplasmic space GO:0030287
The region between the plasma membrane and the cell wall in organisms lacking an outer cell membrane such as yeast and Gram positive bacteria. The region is thinner than the equivalent in Gram negative bacteria.
1 P24031 (/IMP)
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