The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Protein Ste5, Fus3-binding domain
".
FunFam 1: Protein STE5
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
MAP-kinase scaffold activity GO:0005078
The binding activity of a molecule that functions as a physical support for the assembly of a multiprotein mitogen-activated protein kinase (MAPK) complex. Binds multiple kinases of the MAPKKK cascade, and also upstream signaling proteins, permitting those molecules to function in a coordinated way. Bringing together multiple enzymes and their substrates enables the signal to be transduced quickly and efficiently.
|
4 | P32917 (/IDA) P32917 (/IDA) P32917 (/IDA) P32917 (/IDA) |
|
MAP-kinase scaffold activity GO:0005078
The binding activity of a molecule that functions as a physical support for the assembly of a multiprotein mitogen-activated protein kinase (MAPK) complex. Binds multiple kinases of the MAPKKK cascade, and also upstream signaling proteins, permitting those molecules to function in a coordinated way. Bringing together multiple enzymes and their substrates enables the signal to be transduced quickly and efficiently.
|
4 | P32917 (/IPI) P32917 (/IPI) P32917 (/IPI) P32917 (/IPI) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | P32917 (/IPI) P32917 (/IPI) P32917 (/IPI) P32917 (/IPI) |
|
Phosphatidylinositol-4,5-bisphosphate binding GO:0005546
Interacting selectively and non-covalently with phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions.
|
4 | P32917 (/IDA) P32917 (/IDA) P32917 (/IDA) P32917 (/IDA) |
|
G-protein beta-subunit binding GO:0031681
Interacting selectively and non-covalently with a G-protein beta subunit.
|
4 | P32917 (/IPI) P32917 (/IPI) P32917 (/IPI) P32917 (/IPI) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Pheromone-dependent signal transduction involved in conjugation with cellular fusion GO:0000750
A signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion. An example of this process is found in Saccharomyces cerevisiae.
|
4 | P32917 (/IDA) P32917 (/IDA) P32917 (/IDA) P32917 (/IDA) |
|
Invasive growth in response to glucose limitation GO:0001403
A growth pattern exhibited by budding haploid cells under certain growth conditions, in which cells retain the typical axial budding pattern of haploids, but become elongated and fail to separate after division; during growth on a solid substrate, this results in penetration of cells into the agar medium. An example of this process is found in Saccharomyces cerevisiae.
|
4 | P32917 (/IMP) P32917 (/IMP) P32917 (/IMP) P32917 (/IMP) |
|
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
|
4 | P32917 (/IDA) P32917 (/IDA) P32917 (/IDA) P32917 (/IDA) |
|
Regulation of transposition, RNA-mediated GO:0010525
Any process that modulates the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate.
|
4 | P32917 (/IMP) P32917 (/IMP) P32917 (/IMP) P32917 (/IMP) |
|
Negative regulation of MAPK cascade GO:0043409
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade.
|
4 | P32917 (/IMP) P32917 (/IMP) P32917 (/IMP) P32917 (/IMP) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
4 | P32917 (/IDA) P32917 (/IDA) P32917 (/IDA) P32917 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | P32917 (/IDA) P32917 (/IDA) P32917 (/IDA) P32917 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
4 | P32917 (/IMP) P32917 (/IMP) P32917 (/IMP) P32917 (/IMP) |
|
Mating projection tip GO:0043332
The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth.
|
4 | P32917 (/IDA) P32917 (/IDA) P32917 (/IDA) P32917 (/IDA) |
|
Mating projection tip membrane GO:0070867
The portion of the plasma membrane surrounding a mating projection tip.
|
4 | P32917 (/IDA) P32917 (/IDA) P32917 (/IDA) P32917 (/IDA) |