The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 4: Tryptophan synthase beta chain

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
137 P0A2K1 (/IPI) P0A2K1 (/IPI) P0A2K1 (/IPI) P0A2K1 (/IPI) P0A2K1 (/IPI) P0A2K1 (/IPI) P0A2K1 (/IPI) P0A2K1 (/IPI) P0A2K1 (/IPI) P0A2K1 (/IPI)
(127 more)
Tryptophan synthase activity GO:0004834
Catalysis of the reaction: L-serine + (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate + H2O.
78 P00931 (/IDA) P00931 (/IDA) P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA)
(68 more)
Pyridoxal phosphate binding GO:0030170
Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
71 P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA)
(61 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
66 P0A2K1 (/IPI) P0A2K1 (/IPI) P0A2K1 (/IPI) P0A2K1 (/IPI) P0A2K1 (/IPI) P0A2K1 (/IPI) P0A2K1 (/IPI) P0A2K1 (/IPI) P0A2K1 (/IPI) P0A2K1 (/IPI)
(56 more)
Tryptophan synthase activity GO:0004834
Catalysis of the reaction: L-serine + (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate + H2O.
8 P25269 (/ISS) P25269 (/ISS) Q9KST6 (/ISS) Q9KST6 (/ISS) Q9KST6 (/ISS) Q9KST6 (/ISS) Q9KST6 (/ISS) Q9KST6 (/ISS)
Tryptophan synthase activity GO:0004834
Catalysis of the reaction: L-serine + (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate + H2O.
4 P14671 (/IMP) P14671 (/IMP) Q5AZP9 (/IMP) Q5AZP9 (/IMP)
Tryptophan synthase activity GO:0004834
Catalysis of the reaction: L-serine + (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate + H2O.
4 Q5AZP9 (/RCA) Q5AZP9 (/RCA) Q5B1Y6 (/RCA) Q5B1Y6 (/RCA)
Tryptophan synthase activity GO:0004834
Catalysis of the reaction: L-serine + (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate + H2O.
2 Q5AZP9 (/IGI) Q5AZP9 (/IGI)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
2 P14671 (/IPI) P14671 (/IPI)
Tryptophan synthase activity GO:0004834
Catalysis of the reaction: L-serine + (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate + H2O.
1 O13831 (/ISO)

There are 14 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Tryptophan biosynthetic process GO:0000162
The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate.
75 P00931 (/IMP) P00931 (/IMP) P0A879 (/IMP) P0A879 (/IMP) P0A879 (/IMP) P0A879 (/IMP) P0A879 (/IMP) P0A879 (/IMP) P0A879 (/IMP) P0A879 (/IMP)
(65 more)
Aromatic amino acid family biosynthetic process GO:0009073
The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).
71 P0A879 (/IMP) P0A879 (/IMP) P0A879 (/IMP) P0A879 (/IMP) P0A879 (/IMP) P0A879 (/IMP) P0A879 (/IMP) P0A879 (/IMP) P0A879 (/IMP) P0A879 (/IMP)
(61 more)
Tryptophan biosynthetic process GO:0000162
The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate.
9 P07345 (/NAS) P07345 (/NAS) P07345 (/NAS) P07345 (/NAS) P07345 (/NAS) P07345 (/NAS) P07345 (/NAS) P07345 (/NAS) P07345 (/NAS)
Tryptophan biosynthetic process GO:0000162
The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate.
6 Q9KST6 (/ISS) Q9KST6 (/ISS) Q9KST6 (/ISS) Q9KST6 (/ISS) Q9KST6 (/ISS) Q9KST6 (/ISS)
Aromatic amino acid family biosynthetic process GO:0009073
The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).
4 Q5AZP9 (/RCA) Q5AZP9 (/RCA) Q5B1Y6 (/RCA) Q5B1Y6 (/RCA)
Tryptophan biosynthetic process GO:0000162
The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate.
3 P9WFX9 (/IDA) P9WFX9 (/IDA) P9WFX9 (/IDA)
Tryptophan biosynthetic process GO:0000162
The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate.
2 Q5AZP9 (/IGI) Q5AZP9 (/IGI)
Tryptophan biosynthetic process GO:0000162
The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate.
2 P25269 (/TAS) P25269 (/TAS)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
2 P14671 (/IEP) P14671 (/IEP)
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
2 P14671 (/IEP) P14671 (/IEP)
Indoleacetic acid biosynthetic process GO:0009684
The chemical reactions and pathways resulting in the formation of indole-3-acetic acid, a compound which functions as a growth regulator in plants.
2 P14671 (/TAS) P14671 (/TAS)
Cleistothecium development GO:0070791
The process whose specific outcome is the progression of the cleistothecium over time, from its formation to the mature structure. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.
2 Q5AZP9 (/IMP) Q5AZP9 (/IMP)
Cellular response to farnesol GO:0097308
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus.
2 Q5AZP9 (/IEP) Q5AZP9 (/IEP)
Tryptophan biosynthetic process GO:0000162
The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate.
1 O13831 (/ISO)

There are 11 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
71 P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA)
(61 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
71 P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA) P0A879 (/IDA)
(61 more)
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
4 P14671 (/IDA) P14671 (/IDA) P25269 (/IDA) P25269 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 O13831 (/HDA) P00931 (/HDA) P00931 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P00931 (/HDA) P00931 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 P14671 (/IDA) P14671 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
2 P14671 (/IDA) P14671 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
2 P14671 (/ISS) P14671 (/ISS)
Chloroplast envelope GO:0009941
The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
2 P25269 (/IDA) P25269 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 A0A1D8PMH6 (/IDA) A0A1D8PMH6 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O13831 (/HDA)
CATH-Gene3D is a Global Biodata Core Resource Learn more...