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CATH Superfamily 3.40.50.10860

Leucine Dehydrogenase, chain A, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Leucine Dehydrogenase, chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 15: Pentafunctional AROM polypeptide

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Shikimate kinase. [EC: 2.7.1.71]
ATP + shikimate = ADP + shikimate 3-phosphate.
    		 22 A0A0B0DHB1 A0A0B0DHB1 A0A1D9QLW8 A0A1D9QLW8 A6ZY89 A7F7H0 A7F7H0 B0XRM8 B3LGE9 B9WFG1
    (12 more...)
    3-dehydroquinate synthase. [EC: 4.2.3.4]
    3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate.
    • The hydrogen atoms on C-7 of the substrate are retained on C-2 of the products.
    • Formerly EC 4.6.1.3.
    		 22 A0A0B0DHB1 A0A0B0DHB1 A0A1D9QLW8 A0A1D9QLW8 A6ZY89 A7F7H0 A7F7H0 B0XRM8 B3LGE9 B9WFG1
    (12 more...)
    Shikimate dehydrogenase. [EC: 1.1.1.25]
    Shikimate + NADP(+) = 3-dehydroshikimate + NADPH.
    • NAD(+) cannot replace NADP(+).
    • In higher organisms, this enzyme forms part of a multienzyme complex with EC 4.2.1.10.
    		 22 A0A0B0DHB1 A0A0B0DHB1 A0A1D9QLW8 A0A1D9QLW8 A6ZY89 A7F7H0 A7F7H0 B0XRM8 B3LGE9 B9WFG1
    (12 more...)
    3-dehydroquinate dehydratase. [EC: 4.2.1.10]
    3-dehydroquinate = 3-dehydroshikimate + H(2)O.
      		 22 A0A0B0DHB1 A0A0B0DHB1 A0A1D9QLW8 A0A1D9QLW8 A6ZY89 A7F7H0 A7F7H0 B0XRM8 B3LGE9 B9WFG1
      (12 more...)
      3-phosphoshikimate 1-carboxyvinyltransferase. [EC: 2.5.1.19]
      Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O- (1-carboxyvinyl)-3-phosphoshikimate.
        		 22 A0A0B0DHB1 A0A0B0DHB1 A0A1D9QLW8 A0A1D9QLW8 A6ZY89 A7F7H0 A7F7H0 B0XRM8 B3LGE9 B9WFG1
        (12 more...)
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