The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
NadA-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: Quinolinate synthase A

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Quinolinate synthetase A activity GO:0008987
Catalysis of the reaction: iminoaspartate + dihydroxy-acetone-phosphate = quinolinate + 2 H2O + phosphate.
35 P11458 (/IDA) P11458 (/IDA) P11458 (/IDA) P11458 (/IDA) P11458 (/IDA) P11458 (/IDA) P11458 (/IDA) P11458 (/IDA) P11458 (/IDA) P11458 (/IDA)
(25 more)
4 iron, 4 sulfur cluster binding GO:0051539
Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
35 P11458 (/IDA) P11458 (/IDA) P11458 (/IDA) P11458 (/IDA) P11458 (/IDA) P11458 (/IDA) P11458 (/IDA) P11458 (/IDA) P11458 (/IDA) P11458 (/IDA)
(25 more)
Quinolinate synthetase A activity GO:0008987
Catalysis of the reaction: iminoaspartate + dihydroxy-acetone-phosphate = quinolinate + 2 H2O + phosphate.
24 P11458 (/IMP) P11458 (/IMP) P11458 (/IMP) P11458 (/IMP) P11458 (/IMP) P11458 (/IMP) P11458 (/IMP) P11458 (/IMP) P11458 (/IMP) P11458 (/IMP)
(14 more)
4 iron, 4 sulfur cluster binding GO:0051539
Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
24 P11458 (/IMP) P11458 (/IMP) P11458 (/IMP) P11458 (/IMP) P11458 (/IMP) P11458 (/IMP) P11458 (/IMP) P11458 (/IMP) P11458 (/IMP) P11458 (/IMP)
(14 more)
Quinolinate synthetase A activity GO:0008987
Catalysis of the reaction: iminoaspartate + dihydroxy-acetone-phosphate = quinolinate + 2 H2O + phosphate.
7 Q9KR14 (/ISS) Q9KR14 (/ISS) Q9KR14 (/ISS) Q9KR14 (/ISS) Q9KR14 (/ISS) Q9KR14 (/ISS) Q9KR14 (/ISS)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
'de novo' NAD biosynthetic process from aspartate GO:0034628
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
24 P11458 (/IMP) P11458 (/IMP) P11458 (/IMP) P11458 (/IMP) P11458 (/IMP) P11458 (/IMP) P11458 (/IMP) P11458 (/IMP) P11458 (/IMP) P11458 (/IMP)
(14 more)
'de novo' NAD biosynthetic process from aspartate GO:0034628
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
11 P9WJK1 (/IDA) P9WJK1 (/IDA) P9WJK1 (/IDA) P9WJK1 (/IDA) P9WJK1 (/IDA) P9WJK1 (/IDA) P9WJK1 (/IDA) P9WJK1 (/IDA) P9WJK1 (/IDA) P9WJK1 (/IDA)
(1 more)
NADH metabolic process GO:0006734
The chemical reactions and pathways involving reduced nicotinamide adenine dinucleotide (NADH), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.
7 Q9KR14 (/ISS) Q9KR14 (/ISS) Q9KR14 (/ISS) Q9KR14 (/ISS) Q9KR14 (/ISS) Q9KR14 (/ISS) Q9KR14 (/ISS)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
24 P11458 (/IDA) P11458 (/IDA) P11458 (/IDA) P11458 (/IDA) P11458 (/IDA) P11458 (/IDA) P11458 (/IDA) P11458 (/IDA) P11458 (/IDA) P11458 (/IDA)
(14 more)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
11 P9WJK1 (/HDA) P9WJK1 (/HDA) P9WJK1 (/HDA) P9WJK1 (/HDA) P9WJK1 (/HDA) P9WJK1 (/HDA) P9WJK1 (/HDA) P9WJK1 (/HDA) P9WJK1 (/HDA) P9WJK1 (/HDA)
(1 more)
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