The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
ATPase, V1 complex, subunit F
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: V-type proton ATPase subunit F

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
9 P39111 (/IPI) P39111 (/IPI) P39111 (/IPI) P39111 (/IPI) P39111 (/IPI) P39111 (/IPI) P39111 (/IPI) P39111 (/IPI) P39111 (/IPI)
Proton-transporting ATPase activity, rotational mechanism GO:0046961
Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism.
9 P39111 (/TAS) P39111 (/TAS) P39111 (/TAS) P39111 (/TAS) P39111 (/TAS) P39111 (/TAS) P39111 (/TAS) P39111 (/TAS) P39111 (/TAS)
Proton-transporting ATPase activity, rotational mechanism GO:0046961
Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism.
2 A0A1D8PH17 (/ISS) A0A1D8PH17 (/ISS)
Proton-transporting ATPase activity, rotational mechanism GO:0046961
Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism.
1 O43046 (/ISO)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Vacuolar acidification GO:0007035
Any process that reduces the pH of the vacuole, measured by the concentration of the hydrogen ion.
10 O43046 (/TAS) P39111 (/TAS) P39111 (/TAS) P39111 (/TAS) P39111 (/TAS) P39111 (/TAS) P39111 (/TAS) P39111 (/TAS) P39111 (/TAS) P39111 (/TAS)
Cellular metal ion homeostasis GO:0006875
Any process involved in the maintenance of an internal steady state of metal ions at the level of a cell.
2 A0A1D8PH17 (/IMP) A0A1D8PH17 (/IMP)
Vacuolar acidification GO:0007035
Any process that reduces the pH of the vacuole, measured by the concentration of the hydrogen ion.
2 A0A1D8PH17 (/IMP) A0A1D8PH17 (/IMP)
Vacuolar acidification GO:0007035
Any process that reduces the pH of the vacuole, measured by the concentration of the hydrogen ion.
2 A0A1D8PH17 (/ISS) A0A1D8PH17 (/ISS)
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
2 A0A1D8PH17 (/IMP) A0A1D8PH17 (/IMP)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
2 A0A1D8PH17 (/IMP) A0A1D8PH17 (/IMP)
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
2 A0A1D8PH17 (/IMP) A0A1D8PH17 (/IMP)
Filamentous growth of a population of unicellular organisms in response to biotic stimulus GO:0036180
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus.
2 A0A1D8PH17 (/IMP) A0A1D8PH17 (/IMP)
Regulation of filamentous growth of a population of unicellular organisms in response to starvation GO:1900434
Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation.
2 A0A1D8PH17 (/IMP) A0A1D8PH17 (/IMP)
Proton transmembrane transport GO:1902600
The directed movement of a proton across a membrane.
1 O43046 (/IC)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Vacuolar proton-transporting V-type ATPase, V1 domain GO:0000221
The V1 domain of a proton-transporting V-type ATPase found in the vacuolar membrane.
9 P39111 (/TAS) P39111 (/TAS) P39111 (/TAS) P39111 (/TAS) P39111 (/TAS) P39111 (/TAS) P39111 (/TAS) P39111 (/TAS) P39111 (/TAS)
Fungal-type vacuole membrane GO:0000329
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
9 P39111 (/HDA) P39111 (/HDA) P39111 (/HDA) P39111 (/HDA) P39111 (/HDA) P39111 (/HDA) P39111 (/HDA) P39111 (/HDA) P39111 (/HDA)
Fungal-type vacuole membrane GO:0000329
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
9 P39111 (/TAS) P39111 (/TAS) P39111 (/TAS) P39111 (/TAS) P39111 (/TAS) P39111 (/TAS) P39111 (/TAS) P39111 (/TAS) P39111 (/TAS)
Fungal biofilm matrix GO:0062040
An extracellular matrix lying external to fungal cells. The fungal biofilm matrix consists of polysaccharides, proteins, lipids, and nucleic acids. Fungal biofilms mediate adherence to host tissues, and provide protection from host immune defenses.
2 A0A1D8PH17 (/IDA) A0A1D8PH17 (/IDA)
Vacuolar proton-transporting V-type ATPase, V1 domain GO:0000221
The V1 domain of a proton-transporting V-type ATPase found in the vacuolar membrane.
1 O43046 (/ISO)
Fungal-type vacuole membrane GO:0000329
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
1 O43046 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 O43046 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O43046 (/HDA)