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CATH Superfamily 3.40.50.10320

LmbE-like

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
LmbE-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Probable N-acetylglucosaminyl-phosphatidylinositol...

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
N-acetylglucosaminylphosphatidylinositol deacetylase. [EC: 3.5.1.89]
6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H(2)O = 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + acetate.
  • Involved in the second step of glycosylphosphatidylinositol (GPI) anchor formation in all eukaryotes.
  • The enzyme appears to be composed of a single subunit (PIG-L in mammalian cells and GPI12 in Saccharomyces cerevisiae).
  • In some species, the long-chain sn-1-acyl group of the phosphatidyl group is replaced by a long-chain alkyl or alk-1-enyl group.
  • Formerly EC 3.1.1.69.
 4 O35790 Q5SX19 Q9HDW9 Q9Y2B2