The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Toll/interleukin-1 receptor homology (TIR) domain
".
FunFam 31: putative ST2L protein isoform X4
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 0 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Toll-like receptor signaling pathway GO:0002224
Any series of molecular signals generated as a consequence of binding to a toll-like receptor. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.
|
2 | M1ZJW4 (/IDA) S6EPL9 (/IDA) |
|
Protein localization to nucleus GO:0034504
A process in which a protein transports or maintains the localization of another protein to the nucleus.
|
2 | M1ZJW4 (/IDA) S6EPL9 (/IDA) |
|
Negative regulation of NIK/NF-kappaB signaling GO:1901223
Any process that stops, prevents or reduces the frequency, rate or extent of NIK/NF-kappaB signaling.
|
2 | M1ZJW4 (/IDA) S6EPL9 (/IDA) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
2 | M1ZJW4 (/IDA) S6EPL9 (/IDA) |
|
Inclusion body GO:0016234
A discrete intracellular part formed of aggregated molecules such as proteins or other biopolymers.
|
2 | M1ZJW4 (/IDA) S6EPL9 (/IDA) |
|
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
|
2 | M1ZJW4 (/IDA) S6EPL9 (/IDA) |
