The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
HAD superfamily/HAD-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 72: Phosphonoacetaldehyde hydrolase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phosphonoacetaldehyde hydrolase. [EC: 3.11.1.1]
Phosphonoacetaldehyde + H(2)O = acetaldehyde + phosphate.
  • This enzyme destabilizes the C-P bond, by forming an imine between one of its lysine residues and the carbonyl group of the substrate, thus allowing this, normally stable, bond to be broken.
  • The mechanism is similar to that used by EC 4.1.2.13 to break a C-C bond.
1316 A0A0B5XBK1 A0A0B5XBK1 A0A0B5XBK1 A0A0B5XBK1 A0A0B5XBK1 A0A0B5XBK1 A0A0B5XBK1 A0A0B5XBK1 A0A0B5XBK1 A0A0B5XBK1
(1306 more...)
CATH-Gene3D is a Global Biodata Core Resource Learn more...