The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11: 3-ketoacyl-CoA thiolase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
3-hydroxyacyl-CoA dehydrogenase activity GO:0003857
Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H(+).
16 P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA)
(6 more)
Acetyl-CoA C-acyltransferase activity GO:0003988
Catalysis of the reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA.
16 P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA)
(6 more)
Enoyl-CoA hydratase activity GO:0004300
Catalysis of the reaction: (3S)-3-hydroxyacyl-CoA = trans-2-enoyl-CoA + H2O.
16 P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA)
(6 more)
Acetyl-CoA C-acyltransferase activity GO:0003988
Catalysis of the reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA.
8 Q8ECP6 (/ISS) Q9KT59 (/ISS) Q9KT59 (/ISS) Q9KT59 (/ISS) Q9KT59 (/ISS) Q9KT59 (/ISS) Q9KT59 (/ISS) Q9KT59 (/ISS)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Fatty acid beta-oxidation GO:0006635
A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and occurs by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A; the cycle continues until only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
16 P76503 (/IGI) P76503 (/IGI) P76503 (/IGI) P76503 (/IGI) P76503 (/IGI) P76503 (/IGI) P76503 (/IGI) P76503 (/IGI) P76503 (/IGI) P76503 (/IGI)
(6 more)
Fatty acid beta-oxidation, unsaturated, even number GO:0033542
A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
16 P76503 (/IMP) P76503 (/IMP) P76503 (/IMP) P76503 (/IMP) P76503 (/IMP) P76503 (/IMP) P76503 (/IMP) P76503 (/IMP) P76503 (/IMP) P76503 (/IMP)
(6 more)
Fatty acid catabolic process GO:0009062
The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
8 Q8ECP6 (/ISS) Q9KT59 (/ISS) Q9KT59 (/ISS) Q9KT59 (/ISS) Q9KT59 (/ISS) Q9KT59 (/ISS) Q9KT59 (/ISS) Q9KT59 (/ISS)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
16 P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA)
(6 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
16 P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA) P76503 (/IDA)
(6 more)
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