The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Peptidase M60, enhancin-like domain 2
".
FunFam 1: TRPM8 channel-associated factor 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q6QR59 (/IPI) Q9Y4C2 (/IPI) |
|
Ion channel binding GO:0044325
Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
|
2 | A6NFQ2 (/IDA) Q9Y4C2 (/IDA) |
|
Ion channel binding GO:0044325
Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
|
2 | A6NFQ2 (/IPI) Q9Y4C2 (/IPI) |
|
Ion channel binding GO:0044325
Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
|
2 | Q8BNE1 (/ISO) Q921K8 (/ISO) |
There are 11 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of protein targeting to membrane GO:0090314
Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
|
2 | A6NFQ2 (/IMP) Q9Y4C2 (/IMP) |
|
Positive regulation of protein targeting to membrane GO:0090314
Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
|
2 | Q8BNE1 (/ISO) Q921K8 (/ISO) |
|
Hematopoietic progenitor cell differentiation GO:0002244
The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.
|
1 | Q921K8 (/IGI) |
|
Negative regulation of anion channel activity GO:0010360
Any process that stops, prevents, or reduces the frequency, rate, or extent of the anion channel activity.
|
1 | A6NFQ2 (/IDA) |
|
Negative regulation of anion channel activity GO:0010360
Any process that stops, prevents, or reduces the frequency, rate, or extent of the anion channel activity.
|
1 | Q921K8 (/ISO) |
|
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
|
1 | A6NFQ2 (/IDA) |
|
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
|
1 | Q921K8 (/ISO) |
|
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
|
1 | Q9Y4C2 (/IDA) |
|
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
|
1 | Q8BNE1 (/ISO) |
|
Positive regulation of anion channel activity GO:1901529
Any process that activates or increases the frequency, rate or extent of anion channel activity.
|
1 | Q9Y4C2 (/IDA) |
|
Positive regulation of anion channel activity GO:1901529
Any process that activates or increases the frequency, rate or extent of anion channel activity.
|
1 | Q8BNE1 (/ISO) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
3 | A0A1B0GVM2 (/IDA) A6NFQ2 (/IDA) Q9Y4C2 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q8BNE1 (/ISO) Q921K8 (/ISO) |
|
Cell junction GO:0030054
A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.
|
2 | A0A1B0GVM2 (/IDA) A6NFQ2 (/IDA) |
|
Cell junction GO:0030054
A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.
|
1 | Q921K8 (/ISO) |