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CATH Superfamily 3.40.390.10

Collagenase (Catalytic Domain)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Collagenase (Catalytic Domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 82: Neutral protease 2

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Deuterolysin. [EC: 3.4.24.39]
Preferential cleavage of bonds with hydrophobic residues in P1'. Also 3-Asn-|-Gln-4 and 8-Gly-|-Ser-9 bonds in insulin B chain.
  • Proteolytic activity found in Penicillium roqueforti, P.caseicolum, Aspergillus sojae and A.oryzae.
  • Optimum pH of 5 for digesting various proteins.
  • Strong action on protamine and histones.
  • Insensitive to phosphoramidon.
  • A distinct A.sojae endopeptidase is larger and has neutral pH optimum.
  • Belongs to peptidase family M35.
  • Formerly EC 3.4.24.4.
 2 B8NWE1 P46076