The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Collagenase (Catalytic Domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 53: Metalloendopeptidase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Metalloendopeptidase activity GO:0004222
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
1 Q9VC47 (/IDA)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Defasciculation of motor neuron axon GO:0007415
Separation of a motor axon away from a bundle of axons known as a fascicle.
10 Q23995 (/IMP) Q24132 (/IMP) Q49II0 (/IMP) Q49II5 (/IMP) Q49II7 (/IMP) Q49II8 (/IMP) Q49IJ0 (/IMP) Q49IJ1 (/IMP) Q49IK4 (/IMP) Q9VC47 (/IMP)
Motor neuron axon guidance GO:0008045
The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues.
10 Q23995 (/IMP) Q24132 (/IMP) Q49II0 (/IMP) Q49II5 (/IMP) Q49II7 (/IMP) Q49II8 (/IMP) Q49IJ0 (/IMP) Q49IJ1 (/IMP) Q49IK4 (/IMP) Q9VC47 (/IMP)
Imaginal disc-derived wing vein morphogenesis GO:0008586
The process in which anatomical structures of the veins on an imaginal disc-derived wing are generated and organized.
10 Q23995 (/IMP) Q24132 (/IMP) Q49II0 (/IMP) Q49II5 (/IMP) Q49II7 (/IMP) Q49II8 (/IMP) Q49IJ0 (/IMP) Q49IJ1 (/IMP) Q49IK4 (/IMP) Q9VC47 (/IMP)
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
1 Q9VC47 (/IMP)
Protein processing GO:0016485
Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
1 Q9VC47 (/IDA)
Positive regulation of BMP signaling pathway GO:0030513
Any process that activates or increases the frequency, rate or extent of BMP signaling pathway activity.
1 Q9VC47 (/IGI)
Positive regulation of activin receptor signaling pathway GO:0032927
Any process that activates or increases the frequency, rate or extent of the activity of any activin receptor signaling pathway.
1 Q9VC47 (/IDA)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 Q9VC47 (/IDA)
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