The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
CAP
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 12: Secreted protein PRY1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Sterol binding GO:0032934
Interacting selectively and non-covalently with a sterol, any steroid containing a hydroxy group in the 3 position, closely related to cholestan-3-ol.
15 P36110 (/IDA) P36110 (/IDA) P36110 (/IDA) P36110 (/IDA) P36110 (/IDA) P36110 (/IDA) P36110 (/IDA) P47032 (/IDA) P47032 (/IDA) P47032 (/IDA)
(5 more)
Cholesterol binding GO:0015485
Interacting selectively and non-covalently with cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
13 P47032 (/IDA) P47032 (/IDA) P47032 (/IDA) P47032 (/IDA) P47032 (/IDA) P47032 (/IDA) P47032 (/IDA) P47032 (/IDA) Q59ZX3 (/IDA) Q59ZX3 (/IDA)
(3 more)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
8 P47032 (/IDA) P47032 (/IDA) P47032 (/IDA) P47032 (/IDA) P47032 (/IDA) P47032 (/IDA) P47032 (/IDA) P47032 (/IDA)
Sterol binding GO:0032934
Interacting selectively and non-covalently with a sterol, any steroid containing a hydroxy group in the 3 position, closely related to cholestan-3-ol.
8 P47032 (/IMP) P47032 (/IMP) P47032 (/IMP) P47032 (/IMP) P47032 (/IMP) P47032 (/IMP) P47032 (/IMP) P47032 (/IMP)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Sterol transport GO:0015918
The directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
17 P36110 (/IMP) P36110 (/IMP) P36110 (/IMP) P36110 (/IMP) P36110 (/IMP) P36110 (/IMP) P36110 (/IMP) P47032 (/IMP) P47032 (/IMP) P47032 (/IMP)
(7 more)
Sterol transport GO:0015918
The directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
15 P36110 (/IGI) P36110 (/IGI) P36110 (/IGI) P36110 (/IGI) P36110 (/IGI) P36110 (/IGI) P36110 (/IGI) P47032 (/IGI) P47032 (/IGI) P47032 (/IGI)
(5 more)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
5 Q59ZX3 (/IMP) Q59ZX3 (/IMP) Q5AB48 (/IMP) Q5AB48 (/IMP) Q5AB48 (/IMP)
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
3 Q5AB48 (/IMP) Q5AB48 (/IMP) Q5AB48 (/IMP)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
21 P36110 (/IDA) P36110 (/IDA) P36110 (/IDA) P36110 (/IDA) P36110 (/IDA) P36110 (/IDA) P36110 (/IDA) P47032 (/IDA) P47032 (/IDA) P47032 (/IDA)
(11 more)
Fungal-type vacuole GO:0000324
A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure.
15 P36110 (/HDA) P36110 (/HDA) P36110 (/HDA) P36110 (/HDA) P36110 (/HDA) P36110 (/HDA) P36110 (/HDA) P47032 (/HDA) P47032 (/HDA) P47032 (/HDA)
(5 more)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
15 P36110 (/HDA) P36110 (/HDA) P36110 (/HDA) P36110 (/HDA) P36110 (/HDA) P36110 (/HDA) P36110 (/HDA) P47032 (/HDA) P47032 (/HDA) P47032 (/HDA)
(5 more)
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
8 P47032 (/HDA) P47032 (/HDA) P47032 (/HDA) P47032 (/HDA) P47032 (/HDA) P47032 (/HDA) P47032 (/HDA) P47032 (/HDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
6 G8BL72 (/IDA) Q59ZX3 (/IDA) Q59ZX3 (/IDA) Q5AB48 (/IDA) Q5AB48 (/IDA) Q5AB48 (/IDA)
Fungal-type cell wall GO:0009277
A rigid yet dynamic structure surrounding the plasma membrane that affords protection from stresses and contributes to cell morphogenesis, consisting of extensively cross-linked glycoproteins and carbohydrates. The glycoproteins may be modified with N- or O-linked carbohydrates, or glycosylphosphatidylinositol (GPI) anchors; the polysaccharides are primarily branched glucans, including beta-linked and alpha-linked glucans, and may also include chitin and other carbohydrate polymers, but not cellulose or pectin. Enzymes involved in cell wall biosynthesis are also found in the cell wall. Note that some forms of fungi develop a capsule outside of the cell wall under certain circumstances; this is considered a separate structure.
2 P47033 (/IDA) P47033 (/IDA)
Yeast-form cell wall GO:0030445
The wall surrounding a cell of a dimorphic fungus growing in the single-cell budding yeast form, in contrast to the filamentous or hyphal form.
2 Q59ZX3 (/IDA) Q59ZX3 (/IDA)
Cell periphery GO:0071944
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
2 P47033 (/HDA) P47033 (/HDA)
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