The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Aldehyde Dehydrogenase; Chain A, domain 2
".
FunFam 21: Aldehyde dehydrogenase family 8 member A1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Retinal dehydrogenase activity GO:0001758
Catalysis of the reaction: retinal + NAD+ + H2O = retinoate + NADH. Acts on both 11-trans and 13-cis forms of retinal.
|
2 | Q8BH00 (/IDA) Q9H2A2 (/IDA) |
|
Retinal dehydrogenase activity GO:0001758
Catalysis of the reaction: retinal + NAD+ + H2O = retinoate + NADH. Acts on both 11-trans and 13-cis forms of retinal.
|
2 | Q0P5F9 (/ISS) Q8BH00 (/ISS) |
|
Retinal dehydrogenase activity GO:0001758
Catalysis of the reaction: retinal + NAD+ + H2O = retinoate + NADH. Acts on both 11-trans and 13-cis forms of retinal.
|
1 | Q8BH00 (/ISO) |
|
Retinal dehydrogenase activity GO:0001758
Catalysis of the reaction: retinal + NAD+ + H2O = retinoate + NADH. Acts on both 11-trans and 13-cis forms of retinal.
|
1 | Q9H2A2 (/TAS) |
|
Aldehyde dehydrogenase (NAD) activity GO:0004029
Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+.
|
1 | Q54QC5 (/ISS) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Liver development GO:0001889
The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.
|
2 | Q66I21 (/IMP) Q66I21 (/IMP) |
|
Retinoic acid metabolic process GO:0042573
The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A.
|
2 | Q0P5F9 (/ISS) Q8BH00 (/ISS) |
|
Retinal metabolic process GO:0042574
The chemical reactions and pathways involving retinal, a compound that plays an important role in the visual process in most vertebrates. In the retina, retinal combines with opsins to form visual pigments. Retinal is one of the forms of vitamin A.
|
2 | Q0P5F9 (/ISS) Q8BH00 (/ISS) |
|
Retinoic acid metabolic process GO:0042573
The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A.
|
1 | Q9H2A2 (/IDA) |
|
Retinoic acid metabolic process GO:0042573
The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A.
|
1 | Q8BH00 (/ISO) |
|
Retinal metabolic process GO:0042574
The chemical reactions and pathways involving retinal, a compound that plays an important role in the visual process in most vertebrates. In the retina, retinal combines with opsins to form visual pigments. Retinal is one of the forms of vitamin A.
|
1 | Q8BH00 (/IC) |
|
Retinal metabolic process GO:0042574
The chemical reactions and pathways involving retinal, a compound that plays an important role in the visual process in most vertebrates. In the retina, retinal combines with opsins to form visual pigments. Retinal is one of the forms of vitamin A.
|
1 | Q9H2A2 (/IDA) |
|
Retinal metabolic process GO:0042574
The chemical reactions and pathways involving retinal, a compound that plays an important role in the visual process in most vertebrates. In the retina, retinal combines with opsins to form visual pigments. Retinal is one of the forms of vitamin A.
|
1 | Q8BH00 (/ISO) |
|
9-cis-retinoic acid biosynthetic process GO:0042904
The chemical reactions and pathways resulting in the formation of 9-cis-retinoic acid, a metabolically active vitamin A derivative.
|
1 | Q8BH00 (/IDA) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9H2A2 (/TAS) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | Q9H2A2 (/HDA) |
