The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aldehyde Dehydrogenase; Chain A, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 14: NAD/NADP-dependent betaine aldehyde dehydrogenase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Betaine-aldehyde dehydrogenase activity GO:0008802
Catalysis of the reaction: betaine aldehyde + NAD+ + H2O = betaine + NADH + H+.
24 P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA)
(14 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
21 P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA)
(11 more)
Betaine-aldehyde dehydrogenase activity GO:0008802
Catalysis of the reaction: betaine aldehyde + NAD+ + H2O = betaine + NADH + H+.
9 Q88AE9 (/ISS) Q88AE9 (/ISS) Q88AE9 (/ISS) Q88AE9 (/ISS) Q88AE9 (/ISS) Q88AE9 (/ISS) Q88AE9 (/ISS) Q88AE9 (/ISS) Q88AE9 (/ISS)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to osmotic stress GO:0006970
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
21 P17445 (/IEP) P17445 (/IEP) P17445 (/IEP) P17445 (/IEP) P17445 (/IEP) P17445 (/IEP) P17445 (/IEP) P17445 (/IEP) P17445 (/IEP) P17445 (/IEP)
(11 more)
Response to X-ray GO:0010165
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).
21 P17445 (/IMP) P17445 (/IMP) P17445 (/IMP) P17445 (/IMP) P17445 (/IMP) P17445 (/IMP) P17445 (/IMP) P17445 (/IMP) P17445 (/IMP) P17445 (/IMP)
(11 more)
Glycine betaine biosynthetic process from choline GO:0019285
The chemical reactions and pathways resulting in the formation of betaine (N-trimethylglycine) from the oxidation of choline.
21 P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA)
(11 more)
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
21 P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA)
(11 more)
Fermentation GO:0006113
The anaerobic enzymatic conversion of organic compounds, especially carbohydrates, coupling the oxidation and reduction of NAD/H and the generation of adenosine triphosphate (ATP).
9 Q88AE9 (/ISS) Q88AE9 (/ISS) Q88AE9 (/ISS) Q88AE9 (/ISS) Q88AE9 (/ISS) Q88AE9 (/ISS) Q88AE9 (/ISS) Q88AE9 (/ISS) Q88AE9 (/ISS)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
21 P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA) P17445 (/IDA)
(11 more)
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