The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Glutaredoxin
".
FunFam 92: Monothiol glutaredoxin
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
6 | O74790 (/IPI) P32642 (/IPI) P32642 (/IPI) Q03835 (/IPI) Q9VJZ6 (/IPI) Q9ZPH2 (/IPI) |
RNA polymerase II activating transcription factor binding GO:0001102
Interacting selectively and non-covalently with an RNA polymerase II transcription activating factor, a protein involved in positive regulation of transcription.
|
3 | P32642 (/IPI) P32642 (/IPI) Q03835 (/IPI) |
Disulfide oxidoreductase activity GO:0015036
Catalysis of the reaction: substrate with reduced sulfide groups = substrate with oxidized disulfide bonds.
|
3 | P32642 (/IMP) P32642 (/IMP) Q03835 (/IMP) |
Glutathione disulfide oxidoreductase activity GO:0015038
Catalysis of the reaction: 2 glutathione + electron acceptor = glutathione disulfide + electron donor.
|
1 | O74790 (/IMP) |
2 iron, 2 sulfur cluster binding GO:0051537
Interacting selectively and non-covalently with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.
|
1 | O74790 (/IDA) |
Protein sequestering activity GO:0140311
The selective interaction of a protein with a specific protein, thereby preventing it from interacting with other partners or inhibiting its localization to other areas of the cell.
|
1 | O74790 (/EXP) |
There are 15 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cellular iron ion homeostasis GO:0006879
Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell.
|
4 | O74790 (/IGI) P32642 (/IGI) P32642 (/IGI) Q03835 (/IGI) |
Cellular iron ion homeostasis GO:0006879
Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell.
|
3 | P32642 (/IPI) P32642 (/IPI) Q03835 (/IPI) |
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
|
3 | P32642 (/IMP) P32642 (/IMP) Q03835 (/IMP) |
Positive regulation of histone deacetylation GO:0031065
Any process that activates or increases the frequency, rate or extent of the removal of acetyl groups from histones.
|
3 | P32642 (/IMP) P32642 (/IMP) Q03835 (/IMP) |
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
3 | P32642 (/IMP) P32642 (/IMP) Q03835 (/IMP) |
Negative regulation of transcription regulatory region DNA binding GO:2000678
Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding.
|
3 | P32642 (/IMP) P32642 (/IMP) Q03835 (/IMP) |
Cellular iron ion homeostasis GO:0006879
Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell.
|
1 | O74790 (/IMP) |
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
|
1 | Q9ZPH2 (/IMP) |
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
|
1 | Q9ZPH2 (/IMP) |
Auxin polar transport GO:0009926
The unidirectional movement of auxin in the stem from tip to base along the vector of gravity or basipetally.
|
1 | Q9ZPH2 (/IMP) |
[4Fe-4S] cluster assembly GO:0044572
The incorporation of four iron atoms and four sulfur atoms into an iron-sulfur cluster.
|
1 | O74790 (/ISO) |
Protein maturation GO:0051604
Any process leading to the attainment of the full functional capacity of a protein.
|
1 | O74790 (/ISO) |
Regulation of cell cycle GO:0051726
Any process that modulates the rate or extent of progression through the cell cycle.
|
1 | Q9ZPH2 (/IEP) |
Reactive oxygen species metabolic process GO:0072593
The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
|
1 | Q9ZPH2 (/IMP) |
Negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding GO:1903026
Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding.
|
1 | O74790 (/IMP) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
4 | O74790 (/IDA) P32642 (/IDA) P32642 (/IDA) Q03835 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
3 | O74790 (/IDA) Q03835 (/IDA) Q9ZPH2 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | O74790 (/HDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | O74790 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | O74790 (/HDA) |