The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Glutaredoxin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 25: Glutathione peroxidase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Glutathione peroxidase. [EC: 1.11.1.9]
2 glutathione + H(2)O(2) = glutathione disulfide + 2 H(2)O.
  • Steroid and lipid hydroperoxides, but not the product of reaction of EC 1.13.11.12 on phospholipids, can act as acceptor, but more slowly than H(2)O(2) (cf. EC 1.11.1.12).
15 A0A178VXC8 A0A178VXC8 A0A178VYF3 A0A178VYF3 O04922 O04922 O22850 Q0WTE6 Q0WTE6 Q8L910
(5 more...)
Phospholipid-hydroperoxide glutathione peroxidase. [EC: 1.11.1.12]
2 glutathione + a hydroperoxy-fatty-acyl-[lipid] = glutathione disulfide + a hydroxy-fatty-acyl-[lipid] + H(2)O.
  • The products of action of EC 1.13.11.12 on phospholipids can act as acceptor; H(2)O(2) can also act, but much more slowly (cf. EC 1.11.1.9).
6 O24031 O48646 O49069 P30708 P52032 Q9FXS3
CATH-Gene3D is a Global Biodata Core Resource Learn more...