The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Glutaredoxin
".
FunFam 248: Thioredoxin
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Disulfide oxidoreductase activity GO:0015036
Catalysis of the reaction: substrate with reduced sulfide groups = substrate with oxidized disulfide bonds.
|
16 |
P25372 (/IDA)
P25372 (/IDA)
P25372 (/IDA)
P25372 (/IDA)
P25372 (/IDA)
P25372 (/IDA)
P25372 (/IDA)
P25372 (/IDA)
Q38FJ1 (/IDA)
Q38FJ1 (/IDA)
(6 more) |
|
Protein disulfide isomerase activity GO:0003756
Catalysis of the rearrangement of both intrachain and interchain disulfide bonds in proteins.
|
8 | Q38FJ1 (/IDA) Q38FJ1 (/IDA) Q38FJ1 (/IDA) Q38FJ1 (/IDA) Q9NG23 (/IDA) Q9NG23 (/IDA) Q9NG23 (/IDA) Q9NG23 (/IDA) |
|
Protein disulfide oxidoreductase activity GO:0015035
Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.
|
1 | O94504 (/IGI) |
|
Protein disulfide oxidoreductase activity GO:0015035
Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.
|
1 | O94504 (/IMP) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
8 | P25372 (/IMP) P25372 (/IMP) P25372 (/IMP) P25372 (/IMP) P25372 (/IMP) P25372 (/IMP) P25372 (/IMP) P25372 (/IMP) |
|
Cell redox homeostasis GO:0045454
Any process that maintains the redox environment of a cell or compartment within a cell.
|
8 | Q38FJ1 (/TAS) Q38FJ1 (/TAS) Q38FJ1 (/TAS) Q38FJ1 (/TAS) Q9NG23 (/TAS) Q9NG23 (/TAS) Q9NG23 (/TAS) Q9NG23 (/TAS) |
|
Cell redox homeostasis GO:0045454
Any process that maintains the redox environment of a cell or compartment within a cell.
|
1 | O94504 (/IGI) |
|
Cell redox homeostasis GO:0045454
Any process that maintains the redox environment of a cell or compartment within a cell.
|
1 | O94504 (/IMP) |
|
Cellular detoxification GO:1990748
Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.
|
1 | O94504 (/NAS) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
17 |
O94504 (/IDA)
P25372 (/IDA)
P25372 (/IDA)
P25372 (/IDA)
P25372 (/IDA)
P25372 (/IDA)
P25372 (/IDA)
P25372 (/IDA)
P25372 (/IDA)
Q38FJ1 (/IDA)
(7 more) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
9 | O94504 (/HDA) P25372 (/HDA) P25372 (/HDA) P25372 (/HDA) P25372 (/HDA) P25372 (/HDA) P25372 (/HDA) P25372 (/HDA) P25372 (/HDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | E9AC16 (/ISO) |
