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CATH Superfamily 3.40.30.10

Glutaredoxin

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Glutaredoxin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 243: Prostamide/prostaglandin F synthase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Prostamide/prostaglandin F(2-alpha) synthase. [EC: 1.11.1.20]
Thioredoxin + prostaglandin H(2) = thioredoxin disulfide + prostaglandin F(2-alpha).
  • The enzyme contains a thioredoxin-type disulfide as a catalytic group.
  • Prostamide H(2) and prostaglandin H(2) are the best substrates; the latter is converted to prostaglandin F(2-alpha).
  • The enzyme also reduces tert-butyl hydroperoxide, cumene hydroperoxide and H(2)O(2), but not prostaglandin D(2) or prostaglandin E(2).
 11 A0A1L8FMM1 A0A1L8FMM1 A0A1S3P2L7 A0A1S3P2L7 B5X9L9 B5X9L9 C1C416 Q28IJ3 Q6AZG8 Q6AZG8
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