The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Glutaredoxin
".
FunFam 194: Iodothyronine deiodinase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 9 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Thyroxine 5'-deiodinase activity GO:0004800
Catalysis of the reaction: 3,5,3'-L-triiodo-L-thyronine + iodide + acceptor + H+ = L-thyroxine + donor-H2.
|
5 | P49896 (/ISS) P79747 (/ISS) Q5I3B2 (/ISS) Q6QN12 (/ISS) Q8UVX8 (/ISS) |
|
Thyroxine 5'-deiodinase activity GO:0004800
Catalysis of the reaction: 3,5,3'-L-triiodo-L-thyronine + iodide + acceptor + H+ = L-thyroxine + donor-H2.
|
4 | P70551 (/IDA) Q92813 (/IDA) Q9IAX2 (/IDA) Q9Z1Y9 (/IDA) |
|
Thyroxine 5'-deiodinase activity GO:0004800
Catalysis of the reaction: 3,5,3'-L-triiodo-L-thyronine + iodide + acceptor + H+ = L-thyroxine + donor-H2.
|
3 | E9QGM3 (/IMP) Q6PBR8 (/IMP) Q9Z1Y9 (/IMP) |
|
Thyroxine 5'-deiodinase activity GO:0004800
Catalysis of the reaction: 3,5,3'-L-triiodo-L-thyronine + iodide + acceptor + H+ = L-thyroxine + donor-H2.
|
1 | Q9Z1Y9 (/ISO) |
|
Thyroxine 5'-deiodinase activity GO:0004800
Catalysis of the reaction: 3,5,3'-L-triiodo-L-thyronine + iodide + acceptor + H+ = L-thyroxine + donor-H2.
|
1 | Q92813 (/TAS) |
|
Selenium binding GO:0008430
Interacting selectively and non-covalently with selenium (Se).
|
1 | Q92813 (/IC) |
|
Selenium binding GO:0008430
Interacting selectively and non-covalently with selenium (Se).
|
1 | Q92813 (/TAS) |
|
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
|
1 | Q92813 (/IPI) |
|
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
|
1 | Q9Z1Y9 (/ISO) |
There are 21 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Thyroid hormone metabolic process GO:0042403
The chemical reactions and pathways involving any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.
|
5 | P49896 (/ISS) P79747 (/ISS) Q5I3B2 (/ISS) Q6QN12 (/ISS) Q8UVX8 (/ISS) |
|
Reproduction GO:0000003
The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms.
|
2 | E9QGM3 (/IMP) Q6PBR8 (/IMP) |
|
Thyroid hormone generation GO:0006590
The formation of either of the compounds secreted by the thyroid gland, mainly thyroxine and triiodothyronine. This is achieved by the iodination and joining of tyrosine molecules to form the precursor thyroglobin, proteolysis of this precursor gives rise to the thyroid hormones.
|
2 | P70551 (/IDA) Q9IAX2 (/IDA) |
|
Response to hormone GO:0009725
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.
|
2 | E9QGM3 (/IDA) Q6PBR8 (/IDA) |
|
Thyroid hormone metabolic process GO:0042403
The chemical reactions and pathways involving any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.
|
2 | P70551 (/IDA) Q92813 (/IDA) |
|
Chordate embryonic development GO:0043009
The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.
|
2 | E9QGM3 (/IMP) Q6PBR8 (/IMP) |
|
Developmental pigmentation GO:0048066
The developmental process that results in the deposition of coloring matter in an organism, tissue or cell.
|
2 | E9QGM3 (/IMP) Q6PBR8 (/IMP) |
|
Developmental growth GO:0048589
The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another.
|
2 | E9QGM3 (/IMP) Q6PBR8 (/IMP) |
|
Regulation of neural retina development GO:0061074
Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.
|
2 | E9QGM3 (/IGI) Q6PBR8 (/IGI) |
|
Positive regulation of cold-induced thermogenesis GO:0120162
Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.
|
2 | P70551 (/ISS) Q92813 (/ISS) |
|
Selenocysteine incorporation GO:0001514
The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation; it is not a posttranslational modification of peptidyl-cysteine.
|
1 | Q92813 (/NAS) |
|
Thyroid hormone generation GO:0006590
The formation of either of the compounds secreted by the thyroid gland, mainly thyroxine and triiodothyronine. This is achieved by the iodination and joining of tyrosine molecules to form the precursor thyroglobin, proteolysis of this precursor gives rise to the thyroid hormones.
|
1 | Q9Z1Y9 (/ISO) |
|
Thyroid hormone generation GO:0006590
The formation of either of the compounds secreted by the thyroid gland, mainly thyroxine and triiodothyronine. This is achieved by the iodination and joining of tyrosine molecules to form the precursor thyroglobin, proteolysis of this precursor gives rise to the thyroid hormones.
|
1 | Q92813 (/TAS) |
|
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
|
1 | P70551 (/IDA) |
|
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
|
1 | Q9Z1Y9 (/ISO) |
|
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
|
1 | P70551 (/IEP) |
|
Thyroid hormone metabolic process GO:0042403
The chemical reactions and pathways involving any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.
|
1 | Q9Z1Y9 (/ISO) |
|
Thyroid hormone metabolic process GO:0042403
The chemical reactions and pathways involving any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.
|
1 | P70551 (/TAS) |
|
Thyroid hormone catabolic process GO:0042404
The chemical reactions and pathways resulting in the breakdown of any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.
|
1 | Q9Z1Y9 (/IMP) |
|
Thyroid-stimulating hormone secretion GO:0070460
The regulated release of thyroid-stimulating hormone, a peptide hormone that stimulates the activity of the thyroid gland, from secretory granules in the anterior pituitary.
|
1 | Q9Z1Y9 (/TAS) |
|
Positive regulation of cold-induced thermogenesis GO:0120162
Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.
|
1 | Q9Z1Y9 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q92813 (/TAS) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q92813 (/IC) |
